Effects of Normal Variation in the Rotational Position of the Aortic Root on Hemodynamics and Tissue Biomechanics of the Thoracic Aorta

Purpose Variation in the rotational position of the aortic root relative to the left ventricle is present in normal trileaflet aortic valves. Its impact on the resulting fluid mechanics of blood flow in the thoracic aorta and structural mechanics in the aortic wall are unknown. We aimed to determine the regional hemodynamic and biomechanical differences in different rotational positions of the normal aortic root (clockwise, central, and counterclockwise positions).