Developmental Delay and School Performance Among Retinoblastoma Survivors: Development/school morbidity among retinoblastoma survivors.

Abstract Purpose To describe the academic performance of childhood retinoblastoma (RB) survivors. Design Retrospective cohort study Methods Retrospective chart review of children followed in a survivorship clinic. Results Seventy-three patients with retinoblastoma (median age at diagnosis 9.97 months [range 0.29, 65.1]) were followed for a median of 6.4 years (0.2, 1.76). Forty-eight (65.8%) had unilateral RB. Forty-three (63.0%) received systemic chemotherapy, 57 (78.1%) enucleation. At last follow-up, 5 (6.8%) children had bilateral visual acuity (VA) Conclusion Academic difficulties in childhood RB survivors are associated with chemotherapy treatment, a risk factor independent of VA.