Intravitreal Bevacizumab Therapy for the Treatment of Choroidal Neovascularization Secondary to Angioid Streaks: A Case Report

Purpose: To report a case of choroidal neovascularization (CNV) secondary to angioid streaks that was treated using intravitreal bevacizumab (IVB) injections.Methods: Case report.Results: A 53-year-old man had undergone focal laser photocoagulation for juxtafoveal CNV in his left eye 6 years ago. The macular lesion developed into a scar, and the best-corrected visual acuity (BCVA) of his left eye remained at 20/ 1000 thereafter. However, 3 years ago, he developed blurred vision in his previously CNV-free right eye. The BCVA of his right eye decreased from 20/33 to 20/ 400. Fundus examination showed peripapillary angioid streaks in both eyes, macular CNV with submacular hemorrhages in the right eye, and pigmented macular scars with salmon patches in the left eye. Fluorescein angiography showed active dye leakage from a subfoveal CNV in the right eye. Optical coherence tomography examination showing retinal lesion with subretinal fluid (SRF) further confirmed the diagnosis of CNV. IVB (1.25 mg/0.05 ml) was then injected in his right eye. After IVB injections, the BCVA improved and SRF resolved. During the 3-year follow-up period, the patient received a total of 8 IVB injections in the right eye. At the last follow-up, the BCVA of the right eye and left eye was 20/40 and 20/1000, respectively.Conclusion: Intravitreal injected bevacizumab seems to have a therapeutic effect in that it stabilizes visual acuity and suppresses CNV secondary to angioid streaks.