Myelodysplastic syndrome can propagate from the multipotent progenitor compartment

Evidence of the presence of abnormalities in the primitive hematopoietic stem cells, as well as functional analysis, has demonstrated that Myelodysplastic syndrome (MDS) is propagated by rare and distinct human MDS propagating cells (MDS-PCs) in 5q- and in refractory anemia with ring sideroblastic (