Long-Term Stability of Chitosan-Based Polyplexes

Purpose. There is a lack of information about the long-term stability of chitosan-based polyplexes although a large amount is known as regards transfection efficiency and physicochemical characteristics. The aim of this work is to study the transfection efficiency and physicochemical properties of chitosan-based polyplexes over time when stored at different temperatures in an acetate-buffer at pH 5.5.