Intercellular adhesion molecule-1 enhances the therapeutic effects of MSCs in a dextran sulfate sodium-induced colitis models by promoting MSCs homing to murine colons and spleens

Xin Li,Qian Wang,Li Ding,Yu Xing Wang,Zhi-Dong Zhao,Ning Mao,Chu-Tse Wu,Hua Wang,Heng Zhu,Shou-Bin Ning

Intercellular adhesion molecule-1 enhances the therapeutic effects of MSCs in a dextran sulfate sodium-induced colitis models by promoting MSCs homing to murine colons and spleens

2019

Xin Li
Qian Wang
Li Ding
Yu Xing Wang
Zhi-Dong Zhao
Ning Mao
Chu-Tse Wu
Hua Wang
Heng Zhu
Shou-Bin Ning

Background To investigate the therapeutic effect of intercellular adhesion molecule (ICAM)-1-modified mesenchymal stem cells (MSCs) in a mouse model of inflammatory bowel disease (IBD) induced by dextran sulfate sodium.

Keywords:

Inflammatory bowel disease
Intercellular adhesion molecule
Cell biology
Mesenchymal stem cell
Intercellular Adhesion Molecule-1
Therapeutic effect
Stem cell
Homing (biology)
Colitis
Biology

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