Highly sensitive sulphide mapping in live cells by kinetic spectral analysis of single Au-Ag core-shell nanoparticles

H2S is an important gasotransmitter in many physiological processes but its concentrations are difficult to measure in vivo. Xiong et al. demonstrate that local variations in H2S levels in live cells can be mapped in real time via spectral shift rates of Au-Ag core-shell plasmonic nanoprobes.