Osama Taha

Assiut University

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Mahmoud Abdelaal

University College Dublin

Mohamed Abozeid

Ain Shams University

Mohamed Talaat

University of Massachusetts Lowell

Torsten Olbers

Linköping University

Jon Kristinsson

Oslo University Hospital

Fatma Adel El Sherif

Assiut University

Almantas Maleckas

University of Gothenburg

Adolfo Leyva‐Alvizo

Hospital Zambrano Hellion

Pradeep Chowbey

Max Super Speciality Hospital

Julio Galindo

Hospital Universitario Ramón y Cajal

Cooperative Institutions

University of Birmingham

University College London

Royal London Hospital

South Tyneside and Sunderland NHS Foundation Trust

Imperial College London

Ain Shams University

Assiut University

Sir Ganga Ram Hospital

Collaborative Group (United States)

Max Super Speciality Hospital

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Impact of Abdominal Subcutaneous Fat Reduction on Glycemic Control in Obese Patients with Type 2 Diabetes Mellitus

Bariatric Surgical Practice and Patient Care (2017)

Assem H.K. Abdelhafez Osama Taha Mahmoud Abdelaal Werd Al‐Najim Carel W. le Roux

Background: The effect on type 2 diabetes mellitus (T2DM) when adipose tissue is removed is controversial. This study aimed to evaluate and compare the effect of the abdominoplasty and bariatric surgery on glycemic control in patients with T2DM. Methods: Patients with T2DM undergoing abdominoplasty for cosmesis were studied (n = 25). Subjects were 36.9 ± 1.3 years with a preoperative body mass index (BMI) of 40.6 ± 0.5 kg/m2 and mean glycated hemoglobin (HbA1c) of 7.4% ± 0.2%. Fifteen matched patients undergoing bariatric surgery were selected as a comparator group. Weight, BMI, waist circumference (WC), random blood glucose (RBG), and HbA1c were evaluated at baseline and 3, 6, and 12 months postsurgery. Results: By 12 months, abdominoplasty reduced weight by 5.6 ± 0.3 kg p < 0.01), and HbA1c was reduced to 6.8% ± 0.3% (p < 0.01). After 12 months, bariatric surgery reduced BMI from 42.2 ± 1 kg/m2 to 26.6 ± 0.4 kg/m2 (p < 0.01). HbA1c reduced from 7.9% ± 0.4% to 5.5% ± 0.2% (p < 0.01). WC was similar between both groups at 3 months, although HbA1c reductions were superior after bariatric surgery. Conclusions: Reducing subcutaneous adipose tissue with abdominoplasty results in a small improvement in glycemic control in patients with T2DM. Despite equivalent WC at 3 months, bariatric surgery outperformed abdominoplasty on all metabolic parameters then and thereafter.

Abdominoplasty

Glycated hemoglobin

10.1089/bari.2017.0042

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Citations (1)

Handling of the Covid-19 Pandemic and Its Effects on Bariatric Surgical Practice: Analysis of GENEVA Study Database

Obesity Surgery (2022)

Rishi Singhal Tom Wiggins Sjaak Pouwels Yashasvi Rajeev Brijesh Madhok

The coronavirus disease 2019 (COVID-19) pandemic led to a worldwide suspension of bariatric and metabolic surgery (BMS) services. The current study analyses data on patterns of service delivery, recovery of practices, and protective measures taken during the COVID-19 pandemic by bariatric teams.The current study is a subset analysis of the GENEVA study which was an international cohort study between 01/05/2020 and 31/10/2020. Data were specifically analysed regarding the timing of BMS suspension, patterns of service recovery, and precautionary measures deployed.A total of 527 surgeons from 439 hospitals in 64 countries submitted data regarding their practices and handling of the pandemic. Smaller hospitals (with less than 200 beds) were able to restart BMS programmes more rapidly (time to BMS restart 60.8 ± 38.9 days) than larger institutions (over 2000 beds) (81.3 ± 30.5 days) (p = 0.032). There was a significant difference in the time interval between cessation/reduction and restart of bariatric services between government-funded practices (97.1 ± 76.2 days), combination practices (84.4 ± 47.9 days), and private practices (58.5 ± 38.3 days) (p < 0.001). Precautionary measures adopted included patient segregation, utilisation of personal protective equipment, and preoperative testing. Following service recovery, 40% of the surgeons operated with a reduced capacity. Twenty-two percent gave priority to long waiters, 15.4% gave priority to uncontrolled diabetics, and 7.6% prioritised patients requiring organ transplantation.This study provides global, real-world data regarding the recovery of BMS services following the COVID-19 pandemic.

Pandemic

Personal Protective Equipment

10.1007/s11695-022-06267-7

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Outcomes of Omega Loop Gastric Bypass, 6-Years Experience of 1520 Cases

Obesity Surgery (2017)

Osama Taha Mahmoud Abdelaal Mohamed Abozeid Awny Askalany Mohamed Alaa

10.1007/s11695-017-2623-8

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Citations (72)

Laparoscopic biliopancreatic diversion/duodenal switch or laparoscopic Roux-en-Y gastric bypass for super-obesity—weight loss versus side effects

Surgery for Obesity and Related Diseases (2010)

Anna Laurenius Osama Taha Almantas Maleckas Hans Lönroth Torsten Olbers

Biliopancreatic Diversion

Duodenal switch

Roux-en-Y anastomosis

10.1016/j.soard.2010.03.293

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A Randomized Comparison Between Staple-Line Oversewing Versus No Reinforcement During Laparoscopic Vertical Sleeve Gastrectomy

Obesity Surgery (2017)

Osama Taha Mahmoud Abdelaal Mohamed Talaat Mohamed Abozeid

Sleeve gastrectomy

10.1007/s11695-017-2835-y

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Citations (40)

Eosinophil cationic protein as a diagnostic marker for asthmatic children treated by immunotherapy.

PubMed (2003)

Al-Asfar Kandil Ahmad N. Hasan Osama Taha Hala O. El‐Mesallamy

We estimated the eosinophil cationic protein (ECP) levels in serum and sputum of 20 children with bronchial asthma to find whether it correlates with disease activity and examine the effect of immunotherapy. Ten-age- and sex- matched healthy children were also included. Children were subjected to full history, clinical examination and investigation including skin prick test, chest x-ray, complete blood count, and estimation of eosinophil cationic protein. In addition, examination of sputum to determine the eosinophil count and eosinophil cationic protein level was carried out. Patients were classified into 2 groups (10 patients each) according to the line of treatment used (5 mild and 5 moderate in severity). Group I received pharmacotherapy only and was followed for one year, while group II, received pharmacotherapy plus immunotherapy for one year. A significant increase in eosinophil count and ECP of blood and sputum was found in asthmatic patients as compared to controls. The ECP levels were significantly higher in moderate cases when compared with mild cases. On comparing levels of both eosinophil count and ECP in peripheral blood and sputum, before and one year after treatment, there was a significant reduction after therapy among the two groups of patients. The reduction was significant in group II. On the other hand there was a significant decrease in both symptoms and medication scores after one year of therapy. In conclusion, ECP may be a marker of eosinophilic activity and degranulation that correlates with the severity of bronchial asthma. Immunotherapy may be a good adjuvant therapy for atopic bronchial asthma of childhood.

Pharmacotherapy

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Effect of adding intrathecal morphine to a multimodal analgesic regimen for postoperative pain management after laparoscopic bariatric surgery: a prospective, double-blind, randomized controlled trial

British Journal of Pain (2016)

Fatma Adel El Sherif Ahmed H. Othman Ahmad Mohammad Abd El-Rahman Osama Taha

Background: Pain control after bariatric surgery is a major challenge. Our objective was to study the efficacy and safety of intrathecal (IT) morphine 0.3 mg added to bupivacaine 0.5% for postoperative pain after laparoscopic bariatric surgery. Methods: After local ethics committee approval, 100 morbidly obese patients scheduled for laparoscopic bariatric surgery were enrolled in this study. Patients were randomly assigned into two groups: Group I received IT 0.3 mg morphine (0.3 mL) added to 1.2 mL of bupivacaine 0.5%; Group II received IT 0.3 mL saline added to 1.2 mL of bupivacaine 0.5%, immediately before induction of general anaesthesia. For both groups, 60 mg ketorolac and 1000 mg paracetamol were infused 30 minutes before the end of surgery. After wound closure, 20 mL bupivacaine 0.25% was infiltrated at wound edges. Results: Visual Analogue Scale (VAS) score was significantly lower in group I immediately, 30 minutes and 1 hour postoperatively. Time to first ambulation, return of intestinal sounds and hospital stay were shorter in group I than group II (p < 0.05); total morphine consumption was significantly lower in group I than group II (p < 0.05). Sedation score was significantly higher in group I immediately postoperatively, while at 30 minutes, 1, 2 and 6 hours postoperatively sedation scores were significantly higher in group II. Itching was significantly higher in group I. Conclusion: The addition of IT morphine to a multimodal analgesic regimen after laparoscopic bariatric surgery was an effective and safe method that markedly reduced postoperative pain, systemic opioid consumption and length of hospital stay.

Regimen

Multimodal therapy

10.1177/2049463716668904

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Citations (32)

Staple Line Complications without Reinforcement, with Oversewing and with Buttressing Using Oxidized Regenerated Cellulose in Laparoscopic Sleeve Gastrectomy, Randomized Comparative Study

Bariatric Surgical Practice and Patient Care (2021)

Osama Taha Samia Saied Mohamed Shoeib Mahmoud Abdelaal Mohamed Abozeid

Background: Laparoscopic sleeve gastrectomy (LSG) is currently one of the most commonly performed bariatric procedures. Oversewing is one of most commonly performed techniques for staple line reinforcement. Oxidized regenerated cellulose (ORC) is an effective hemostatic agent with several advantages. This study aims to compare the outcomes of no-reinforcement, staple line oversewing and staple line buttressing with ORC in LSG. Materials and Methods: Patients were randomized into three groups: 100 patients underwent LSG without reinforcement, 100 patients underwent LSG with oversewing of the staple line, and 100 patients underwent LSG with staple line buttressing by using ORC. Results: The mean operative time was longer in patients with staple line oversewing; Group B (53.4 ± 4.21 min) compared with no reinforcement and using the ORC over the staple line (p-value <0.01). The postoperative bleeding is significantly (p < 0.05) reduced with oversewing and with using ORC compared with the control group. Conclusion: Oversewing of the staple line during LSG is a nonexpansive and easy method to decrease bleeding. However, it is time-consuming, associated with a higher incidence of staple line hematoma and postoperative vomiting. Using ORC is effective in reducing staple line bleeding in LSG compared with the control group.

10.1089/bari.2021.0033

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Citations (2)

Role of gastric bypass surgery in control of blood sugar in obese uncontrolled type 2 diabetic patients

Diabetology & Metabolic Syndrome (2024)

Hala Khalf Allah El-Shreef Osama Taha Heba A Abd El Hafeez Amal Ibrahim Abd El-Rheem Abo Shoka

Abstract Background and goal The pandemic of the twenty-first century is diabetes. Both type 2 diabetes mellitus and obesity pose severe problems for public health. Despite significant improvements in diagnosing and managing both conditions, diabetes mellitus remains poorly controlled, and diabetic complications are more common than ever. Internists have discovered over the past 20 years that obese people with type 2 diabetes who have gastric bypass surgery to shed weight have improved glycemic control. Thus, interventional diabetology has a growing significance in patients’ ability to reverse type 2 diabetes mellitus. We want to evaluate the impact of gastric bypass on blood sugar regulation and look for potential causes. Patients and methods Between 2018 and 2020, a prospective interventional study was carried out. Ninety patients in total were enrolled in the trial. The two patient groups (A and B) contained 45 obese T2DM patients with a body mass index (BMI) of over 35 kg/m 2 . Group B received its antidiabetic medications, either oral hypoglycemic or insulin, while Group A underwent gastric bypass surgery. Each patient underwent a comprehensive history review and clinical assessment. Both groups had their HA1c and blood sugar levels measured; group A had their insulin, GLP-1, and HOMA-IR (Homeostasis Model Assessment for Insulin Resistance) levels calculated at time O and one year later. Results The demographic differences between the two study groups were negligible. After a one-year follow-up, group A had significantly lower anthropometric measurement data for BMI and waist circumference (cm), lipid profile data for triglycerides, total cholesterol, and LDL levels, and systolic and diastolic blood pressure. Fasting plasma glucose and HbA1c, two metrics of glucose metabolism, significantly decreased in group A. Regarding indicators of glucose metabolism, there was a drop in fasting insulin level and HOMA-IR and an increase in GLP1 level in the gastric bypass group. Conclusion As a result of improving all indicators, gastric bypass is an effective treatment for patients with uncontrolled T2DM. Future research that is confirmed is needed.

Gastric bypass surgery

Blood sugar

10.1186/s13098-024-01281-4

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Efficacy of Laparoscopic Greater Curvature Plication for Weight Loss and Type 2 Diabetes: 1-Year Follow-Up

Obesity Surgery (2012)

Osama Taha

10.1007/s11695-012-0724-y

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Citations (22)