H. K. Mahmoud

Nasser Institute hospital

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U. W. Schaefer

Klinik Lüneburger Heide

Dietrich W. Beelen

Essen University Hospital

H. Grosse‐Wilde

Essen University Hospital

C. G. Schmidt

Charité - Universitätsmedizin Berlin

Ilias I.N. Doxiadis

University Hospital Leipzig

K. Quabeck

BG Klinikum Duisburg

H. J. Richter

Fraunhofer Institute for Ceramic Technologies and Systems

R. Becher

Klinik und Poliklinik für Urologie

E. Seither

Chirurgische Universitätsklinik Heidelberg

J. van de Loo

Changi General Hospital

Cooperative Institutions

Essen University Hospital

Cairo University

University of Münster

University of Duisburg-Essen

King Faisal Specialist Hospital & Research Centre

Nasser Institute hospital

Klinik und Poliklinik für Urologie

Ludwig-Maximilians-Universität München

Heidelberg University

Medical College of Wisconsin

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Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report

Bone Marrow Transplantation (2008)

Mahmoud Aljurf Syed Ziauddin A. Zaidi Hassan El Solh Fazal Hussain Ardeshir Ghavamzadeh

10.1038/bmt.2008.389

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Citations (51)

Bone Marrow Transplantation in Acute Leukemia

Hämatologie und Bluttransfusion (1987)

U. W. Schaefer Dietrich W. Beelen H. K. Mahmoud K. Quabeck R. Becher

10.1007/978-3-642-71213-5_31

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Citations (3)

Bone marrow transplantation for myeloblastoma

European Journal Of Haematology (1988)

K. Quabeck Dietrich W. Beelen H. K. Mahmoud H. G. Saver Ullrich Graeven

A 20‐yr‐old man with bulky mediastinal and retroperitoneal tumour masses identified as myeloblastoma is described. After a partial remission was induced by aggressive chemotherapy, mediastinal irradiation and retroperitoneal tumour resection, the patient received an allogeneic marrow graft from his HLA‐identical sister. The conditioning regimen consisted of high‐dose busulfan and cyclophosphamide. The patient has a well‐controlled secondary chronic graft‐versus‐host disease. He is in unmaintained complete remission and in good general condition at 20 months post‐transplantation.

Regimen

Total body irradiation

10.1111/j.1600-0609.1988.tb00890.x

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Citations (8)

Higher risk of graft-versus-host-disease in patients with chronic granulocytic leukemia after allogeneic bone marrow transplantation?

Journal of Cancer Research and Clinical Oncology (1986)

Dietrich W. Beelen H. K. Mahmoud W. Hoffmann U. W. Schaefer C. G. Schmidt

Hematology

10.1007/bf02580207

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Citations (0)

INFLUENCE OF UNDERLYING DISEASE AND DONOR SEX ON THE INCIDENCE OF GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC BONE MARROW TRANSPLANTATION

British Journal of Haematology (1987)

Dietrich W. Beelen K. Quabeck H. K. Mahmoud H. Grosse‐Wilde U. W. Schaefer

Hematology

10.1111/j.1365-2141.1987.00379.x-i1

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Citations (3)

INFLUENCE OF UNDERLYING DISEASE AND DONOR SEX ON THE INCIDENCE OF GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC BONE MARROW TRANSPLANTATION

British Journal of Haematology (1987)

Dietrich W. Beelen K. Quabeck H. K. Mahmoud H. Grosse‐Wilde U. W. Schaefer

10.1111/j.1365-2141.1987.tb06880.x

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Citations (2)

The “Clostridial effect” of selective decontamination of the human gut with trimethoprim/sulphamethoxazole in neutropenic patients

Infection (1983)

E. Haralambie H. K. Mahmoud G Linzenmeier F. Wendt

Clostridia

Aerobic bacteria

Trimethoprim

10.1007/bf01641197

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Citations (13)

Toxoplasmosis After Bone Marrow Transplantation

Hämatologie und Bluttransfusion (1987)

Dietrich W. Beelen H. K. Mahmoud M.-L. Mlynek Ulrike Schmidt H. J. Richter

Aplastic anemia

Toxoplasmosis

10.1007/978-3-642-71213-5_104

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Citations (7)

IMMUNE TRANSFER STUDIES IN CANINE ALLOGENEIC MARROW GRAFT DONOR-RECIPIENT PAIRS

Transplantation (1986)

H. Grosse‐Wilde K. Krumbacher F. Schöning Ilias I.N. Doxiadis H. K. Mahmoud

Transfer of immunity occurring with bone marrow grafting was studied using the dog as a preclinical model. Allogeneic bone marrow transplantation (BMT) was performed between DLA-identical beagle littermates. The donors were immunized with tetanus toxoid (TT) or sheep red blood cells (SRBC), and their humoral response was monitored by hemagglutination. The recipients of bone marrow from TT-immunized donors showed a marked increase of antibody titer one week posttransplantation, while in the recipients of marrow from SRBC immunized donors the antibody titers were considerably lower. Within the following 60 days the antibody titers in both groups diminished gradually to pregrafting levels. Control experiments in which cellfree plasma from donors immunized with TT and SRBC respectively was transfused indicated that the initial rise of specific antibody tites after marrow grafting is likely to be due to a passive transfer of humoral, immunity. A single challenge of these marrow graft recipients with the respective antigen 15–18 weeks posttransplantation led to a secondary type of humoral immune response. In addition, it could be demonstrated that transfer of memory against TT or SRBC was independen from the actual antibody titer and the time of vaccination of the donor. One dog was immunized with TT after serving as marrow donor. When the donor had shown an antibody response, a peripheral blood leukocytes (PBL) transfusion was given to his chimera. Subsequent challenge of the latter resulted in a secondary type of specific antibody response. This indicates that specific cellular-bound immunological memory can be transferred after BMT from the donor to his allogneneic bone marrow chimera by transfusion of peripheral blood leukocytes. The data presented may be of importance in clinical BMT to protect patients during the phase of reduced immune reactivity by trnsfer of memory cells from histocompatible immunized donors.

Toxoid

Antibody titer

Humoral immunity

10.1097/00007890-198607000-00014

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Citations (11)

Augenveränderungen nach Knochenmark-Transplantation

Klinische Monatsblätter für Augenheilkunde (1985)

A Nonnenmacher Hendrik Borgmann H. K. Mahmoud U. W. Schaefer

Mit Hilfe der Knochenmark-Transplantation ist es möglich geworden, eine Bluterkrankung wie die akute Leukämie zu heilen. Kommt es zu einer Transplantat-gegen-Wirt-Reaktion, so entstehen bei chronischem Verlauf am Auge typische Veränderungen der Bindehaut, wie sie vom Sjögren-Syndrom und vom Schleimhaut-Pemphigoid bekannt sind. Kasuistisch werden diese ophthalmologischen Komplikationen beschrieben und im Sinne einer Immunreaktion diskutiert.

10.1055/s-2008-1050869

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Citations (3)