Praveen Kumar Sharma

Devi Ahilya Vishwavidyalaya

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Sachin Jain

Devi Ahilya Vishwavidyalaya

Santosh Ghule

Savitribai Phule Pune University

Shivram Sharma

Vikram University

Jitendra Kaushik

MIT Art, Design and Technology University

Shivram Sharma

Neelam Balekar

IPS Academy

Sanjay Choudhary

Shivram Sharma

Devi Ahilya Vishwavidyalaya

Sushil Sharma

Seaweed Energy Solutions (Norway)

Kamal Wadhwa

Cooperative Institutions

IPS Academy

King George's Medical University

All India Institute of Medical Sciences

Devi Ahilya Vishwavidyalaya

Sarojini Naidu Medical College

All India Institute of Medical Sciences Bhopal

Sawai ManSingh Medical College and Hospital

Sanjay Gandhi Post Graduate Institute of Medical Sciences

Creative Commons

Jodhpur National University

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In Vitro Free Radical Scavenging Activity of Gallic Acid Isolated From Caesalpinia Decapetala Wood

Asian Pacific Journal of Tropical Disease (2012)

Upendra Bhadoriya Praveen Kumar Sharma Shailendra Singh Solanki

Antioxidant capacities and phenolic contents of Gallic Acid isolated from plant Caesalpinia decapetala were investigated. Caesalpinia decapetala is a plant used to treat burns, biliousness and stomach disorders. The antioxidant activity was estimated by the ABTS and DPPH methods. The total phenolic was measured using Folin-Ciocalteu assay. Identification of isolated Gallic Acid was also performed by reverse-phase high-performance liquid chromatography (RP-HPLC) using Cosmosil C18 column (150mm × 4.6mm, 5μm particle). The mobile phase was a mixture of ethyl acetate: ethanol: water (1:5:4, v/v/v) delivered at a flow rate of 1.0 mL min-1. The total phenolic content was found to be 4.31% (w/w). Isolation of Gallic Acid with optimum yield was performed using a mixture of solvents (Ethanol: Water 65:35). Isolated Gallic Acid showed significant in vitro free radical scavenging activity in both model; but in ABTS assay significant % inhibition of free radical was observed as compared to DPPH assay. Research concluded that Caesalpinia decapetala extract can be used as potent antioxidant which can play vital role against the diseases like neurodegenerative disorders, inflammation, viral infections and gastric ulcer.

ABTS

Caesalpinia

10.1016/s2222-1808(12)60274-6

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Citations (34)

In vivo anti-inflammatory activity of Tabernaemontana divaricata leaf extract on male albino mice

Chinese Journal of Natural Medicines (2013)

Sachin Jain Praveen Kumar Sharma Santosh Ghule Ankit Jain Nitesh Jain

Croton

Croton oil

Anti-inflammatory

Decoction

Apocynaceae

Aqueous extract

10.1016/s1875-5364(13)60086-2

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Citations (22)

High Performance Smart Temperature Sensor Using Voltage Controlled Ring Oscillator

International Journal of Advanced Engineering Research and Science (2017)

Praveen Kumar Sharma Gajendra Sujediya

In the broadest definition, a sensor is an electronic component, module, or subsystem whose purpose is to detect events or changes in its environment and send the information to other electronics, frequently a computer processor.Temperature is most-measured process variable in the industrial automation.The most commonly, temperature sensor was used to convert the temperature value to the electrical value.The temperature sensors are the key to read the temperatures correctly and to control the temperature in the industrials applications.Such "smart" temperature sensors combine a sensor and interface electronics on the single chip, and are preferably manufactured in a low-cost standard CMOS process.

Ring oscillator

10.22161/ijaers.4.9.2

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Citations (3)

Crystal structure of the complex of proliferating cell nuclear antigen from Leishmania donovani with tetrachloro-L-thyronine at 2.95 Angstrom resolution

P. Singh Satya P. Yadav Praveen Kumar Sharma Punit Kaur S Sharma

Angstrom

10.2210/pdb5f7i/pdb

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Systematic Evaluation of Antiulcer Activity of Herbal Formulation ‘Chandanasava’ in Rats

Asian Pacific Journal of Tropical Disease (2012)

Pankaj Dixit Praveen Kumar Sharma Dinesh Kumar Jain Vikas Jharia

To evaluate three formulations of 'Chandanasava' [commercially made by Baidyanath, Dabur and test (prepared in-house)] for anti-ulcer activity. The activity was evaluated in Albino wistar rats against ethanol induced, aspirin induced, cold restraint induced and pylorus ligation induced gastric ulcer models. The formulations were administered orally at the dose of 6 ml/kg. The percentage inhibition of ulcer formation in the ethanol induced ulcer model 66.51%, 74.76% and 78.85% respectively, in the aspirin induced ulcer model 78.30%, 72.30% and 68.69% respectively; in cold restraint stress ulcer model 78.57%, 76.28% and 73.85% respectively for Baidyanath, Dabur and test formulations. Further, the pylorus ligated rats treated with Chandanasava exhibited significantly (P < 0.001) decreased ulcer lesions, gastric volume, and total acidity. It was found to prevent the ulceration by increasing the pH and mucus secretion in pylorus ligated rats. The formulations of 'Chandanasava' possess significant antiulcer activity in variety of preclinical models and should be further evaluated to substantiate the findings.

Antiulcer drug

10.1016/s2222-1808(12)60150-9

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Citations (5)

Schwarz lemma applications

International Journal of Statistics and Applied Mathematics (2020)

Praveen Kumar Sharma

In this Paper, we have studied the Schwarz’s lemma and arbitrary analytic functions on the open unit disk D and we have proved that range of all the analytic functions on the open unit disk always lies in the closed annulus with centre origin and inner and outer radius depends on the modulus of the function at origin and also discuss its one more application.

Unit disk

Annulus (botany)

Lemma (botany)

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Common fixed points for weak compatible maps in fuzzy metric spaces

International Journal of Applied Mathematical Research (2012)

Praveen Kumar Sharma Sanjay Choudhary Kamal Wadhwa

In this note we shall prove common fixed point theorems for four mappings under weak compatible condition in the setting of fuzzy metric space, fuzzy 2-metric space, and fuzzy 3-metric spaces. Our results generalize the results of Singh, Jain and Jain.

10.14419/ijamr.v1i2.61

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Citations (2)

KEYWORDSHaemophilia, Coagulation Profile, Haemarthrosis, FISH

Rajni Choudhary Praveen Kumar Sharma Rajendra Kumar Nigam Reeni Malik

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DEVELOPMENT AND STUDY OF WOUND HEALING ACTIVITY OF AN AYURVEDIC FORMULATION

Iranian journal of pharmaceutical sciences (2011)

Akansha Jain Shubham Jain Aakash Singh Panwar Ankit Jainb Praveen Kumar Sharma

The effect of prepared Ayurvedic formulation was evaluated on excision and incision wound models in rats. The wound-healing activity was assessed by the rate of period of epithelialization and skin-breaking strength. Histological study of the granulation tissue was carried out to know the extent of collagen formation in the wound tissue. The Ayurvedic formulation prepared was then promoted for woundhealing activity in two wound models. The treated animals showed a significant reduction in the wound area and faster rate of epithialisation. In an incision wound model, formulation treated animals demonstrated a significant skin-breaking strength. Histological studies of the tissue obtained from the formulation treated group revealed that the activity was more significant in this group. Our present study reveals that the Ayurvedic formulation posses a potent wound healing activity, which could be a good choice of remedy for wound healing but less potent than standard nitrofurazone.

Nitrofurazone

Granulation tissue

Breaking strength

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Citations (8)

Determinants of stroke in patients with rhino cerebral mucormycosis seen during the second wave of COVID-19 pandemic: A prospective cohort study

Journal of Infection and Public Health (2022)

Shweta Pandey Hardeep Singh Malhotra Ravindra Kumar Garg Kamini Sharma Imran Rizvi

Rhino cerebral mucormycosis is an uncommon opportunistic infection of the nasal sinuses and brain, and a group of saprophytic fungi causes it. During the second wave of COVID-19, India witnessed an unprecedented number of patients with rhino cerebral mucormycosis. Invasion of the cavernous sinus and occlusion of the internal carotid artery in many cases resulted in a stroke. The study aimed to assess the clinical and neuroimaging predictors of stroke in patients with rhino cerebral mucormycosis. We also evaluated the predictors of death in these patients at 90 days.

Stroke

10.1016/j.jiph.2022.10.009

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Citations (1)