YW

Ying Wu

Tennessee State University

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Dafeng Hui

Tennessee State University

S H Shen

Zhongda Hospital Southeast University

Hui Fang

Nanchang University

Rabia Syed

Tennessee State University

Anto Pradeep Raja Charles

University of Nebraska–Lincoln

Fangping Yu

Songjiang District Central Hospital

H Z Zhang

Chinese Academy of Medical Sciences & Peking Union Medical College

R. Mu

Tennessee State University

Xinfu Zhang

Qingdao Agricultural University

Steve W. Cui

Agriculture and Agri-Food Canada

Cooperative Institutions

Tennessee State University

Chinese Academy of Medical Sciences & Peking Union Medical College

Shanghai Jiao Tong University

Ministry of Agriculture and Rural Affairs

Qingdao Agricultural University

Peking Union Medical College Hospital

Henan University of Science and Technology

Ruijin Hospital

Zhejiang University

Songjiang District Central Hospital

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Electrohydrodynamic processing of natural polymers for active food packaging: A comprehensive review

Comprehensive Reviews in Food Science and Food Safety (2021)

Anto Pradeep Raja Charles Tony Z. Jin R. Mu Ying Wu

The active packaging materials fabricated using natural polymers is increasing in recent years. Electrohydrodynamic processing has drawn attention in active food packaging due to its potential in fabricating materials with advanced structural and functional properties. These materials have the significant capability in enhancing food's quality, safety, and shelf-life. Through electrospinning and electrospray, fibers and particles are encapsulated with bioactive compounds for active packaging applications. Understanding the principle behind electrohydrodynamics provides fundamentals in modulating the material's physicochemical properties based on the operating parameters. This review provides a deep understanding of electrospray and electrospinning, along with their advantages and recent innovations, from food packaging perspectives. The natural polymers suitable for developing active packaging films and coatings through electrohydrodynamics are intensely focused. The critical properties of the packaging system are discussed with characterization techniques. Furthermore, the limitations and prospects for natural polymers and electrohydrodynamic processing in active packaging are summarized.

Electrohydrodynamics

10.1111/1541-4337.12827

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Citations (49)

[Long-term conditional disease-free survival for rectal cancer patients underwent neoadjuvant chemoradiotherapy].

S H Shen Ying Wu Davide Li Qizhu Zhang Lei Feng

Objective: To explore the application value of the conditional disease-free survival (cDFS) analysis in predicting prognosis of stage-specific rectal cancer patients underwent neoadjuvant chemoradiotherapy (nCRT). Methods: Clinicopathologic data of 436 patients with rectal cancer received nCRT and radical operation in Cancer Hospital, Chinese Academy of Medical Sciences between January 2004 and December 2016 were retrospectively reviewed. With reference to conditional probability, the 3-year cDFS of patients at different ypTNM stage after completion of nCRT was estimated using the Kaplan-Meier method. Results: There were 66 patients of ypTNM stage 0 (pathological complete response), 87 patients of ypTNM stage Ⅰ, 135 patients of ypTNM stage Ⅱ and 148 patients of ypTNM stage Ⅲ. The 3-year accumulated DFS of patients with ypTNM stage 0, ypTNM stage Ⅰ, ypTNM stage Ⅱ, and ypTNM stage Ⅲ were 97.0%, 93.1%, 85.2%, and 64.2%, respectively. On the condition of postoperactive disease-free survival for 1 year, 2 years, 3 years, 4 years, and 5 years, the corresponding 3-year cDFS of patients at ypTNM stage 0 were 97.0%, 95.5%, 96.9%, 98.4%, 100.0%, respectively. The corresponding 3-year cDFS of patients at ypTNM Ⅲ were 68.2%, 79.3%, 86.3%, 92.1%, 96.4%, respectively. The more advanced ypTNM staging resulted in the more improvement of 3-year cDFS being acquired. Conclusion: cDFS is a better method to reflect the dynamic changes of the prognosis of rectal cancer patients with nCRT in different ypTNM stage, and it is useful to guide the clinicians to assess the prognosis and propose appropriate surveillance.目的：探讨条件无疾病生存分析在新辅助同步放化疗(nCRT)后不同ypTNM分期直肠癌患者预后预测中的应用价值。方法：回顾性分析2004年1月至2016年12月在中国医学科学院肿瘤医院行nCRT并接受根治性手术的436例直肠癌患者的临床病理资料，结合条件概率定义采用Kaplan-Meier方法计算不同ypTNM分期患者的3年条件无疾病生存率(cDFS)。结果： 0期(获得病理完全缓解)患者66例，ypTNM Ⅰ期患者87例，ypTNM Ⅱ期135例，ypTNM Ⅲ期148例。0期、ypTNM Ⅰ期、ypTNM Ⅱ期、ypTNM Ⅲ期患者的3年累积无疾病生存率分别为97.0%、93.1%、85.2%和64.2%。在患者术后已无疾病生存1、2、3、4和5年的条件下，0期患者相应的3年cDFS分别为97.0%、95.5%、96.9%、98.4%和100%。ypTNM Ⅲ期患者相应的3年cDFS分别为68.2%、79.3%、86.3%、92.1%和96.4%，ypTNM分期越差的患者其3年cDFS改善越大。结论：条件无疾病生存分析更能体现接受nCRT后不同ypTNM分期直肠癌患者预后的动态变化规律，并且可以帮助临床医师更好地对患者进行精准的预后预测并制定合理复查随访策略。.

Chemoradiotherapy

10.3760/cma.j.cn112152-20210105-00013

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Advances and trends in food polysaccharide research

Bioactive Carbohydrates and Dietary Fibre (2022)

10.1016/j.bcdf.2022.100332

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The Association between Distal Findings and Proximal Colorectal Neoplasia: A Systematic Review and Meta-Analysis

The American Journal of Gastroenterology (2017)

Jason L. Huang Y H Wang Johnny Y. Jiang Chengbo Yu Ying Wu

Objectives: Whether screening participants with distal hyperplastic polyps (HPs) detected by flexible sigmoidoscopy (FS) should be followed by subsequent colonoscopy is controversial. We evaluated the association between distal HPs and proximal neoplasia (PN)/advanced proximal neoplasia (APN) in asymptomatic, average-risk patients. Methods: We searched Ovid Medline, EMBASE, and the Cochrane Library from inception to 30 June 2016 and included all screening studies that examined the relationship between different distal findings and PN/APN. Data were independently extracted by two reviewers with disagreements resolved by a third reviewer. We pooled absolute risks and odds ratios (ORs) with a random effects meta-analysis. Seven subgroup analyses were performed according to study characteristics. Heterogeneity was characterized with theI2 statistics. Results: We analyzed 28 studies (104,961 subjects). When compared with normal distal findings, distal HP was not associated with PN (OR=1.16, 95% confidence interval (CI)=0.89–1.51,P=0.14,I2=40%) or APN (OR=1.09, 95% CI=0.87–1.36,P=0.39,I2=5%), while subjects with distal non-advanced or advanced adenoma had higher odds of PN/APN. Higher odds of PN/APN were observed for more severe distal lesions. Weaker association between distal and proximal findings was noticed in studies with higher quality, larger sample size, population-based design, and more stringent endoscopy quality-control measures. The Egger's regression tests showed allP>0.05. Conclusions: Distal HP is not associated with PN/APN in asymptomatic screening population when compared with normal distal findings. Hence, the presence of distal HP alone detected by FS does not automatically indicate colonoscopy referral for all screening participants, as other risk factors of PN/APN should be considered.

Sigmoidoscopy

10.1038/ajg.2017.130

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Application of yellow mustard mucilage and starch in nanoencapsulation of thymol and carvacrol by emulsion electrospray

Carbohydrate Polymers (2022)

Anto Pradeep Raja Charles R. Mu Tony Z. Jin Deyu Li Zhiliang Pan

Nanocapsules

Mucilage

Carvacrol

10.1016/j.carbpol.2022.120148

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Citations (42)

Effect of thermal process on the key aroma components of green tea with chestnut‐like aroma

Journal of the Science of Food and Agriculture (2022)

Fengfeng Qu Xiao‐Han Li Peiqiang Wang Ya‐Hui Han Ying Wu

Chestnut-like aroma is one of the unique qualities of Chinese green tea and has become an important factor influencing consumer decisions. However, the chemical formation mechanism of chestnut-like aroma during green tea processing remains unclear. In this study, the dynamic changes of key components contributing to chestnut-like aroma and their precursors were analyzed in fresh leaves, fixation leaves, first baking tea leaves, and green tea.The thermal process had an important effect on volatile components in tea leaves, causing a significant decrease of alcohols and esters and a significant increase of ketones, acids, phenols, and sulfur compounds. Furthermore, 31 volatiles were identified as the key odorants responsible for chestnut-like aroma of green tea, including dimethyl sulfide, methyl isobutenyl ketone, 2-methylbutanal, 2,4-dimethylstyrene, d-limonene, methyl 2-methylvalerate, linalool, decanal, longifolene, phenylethyl alcohol, l-α-terpineol, jasmone, and so on. And the majority of these odorants were only formed in the drying stage. Additionally, isoleucine, theanine, methionine, and glucose were found to be involved in the formation of chestnut-like aroma of green tea.The drying process played a vital important role in the formation of chestnut-like aroma of green tea. © 2022 Society of Chemical Industry.

10.1002/jsfa.12177

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Citations (22)

Clinical Application of Intracranial Pressure Monitoring Based on Flash Visual Evoked Potential in Treatment of Patients with Hypertensive Intracerebral Hemorrhage

Research Square (Research Square) (2020)

Fangping Yu Yingchun Zhao Yu Zhang Xinghua Luan Ying Wu

Abstract Objective To investigate the application value of flash visual evoked potential (FVEP) noninvasive intracranial pressure (nICP) monitoring technology in patients with hypertensive intracerebral hemorrhage (HICH). Methods There were 116 eligible subjects included in the experiment, the final sample size was 102 for this study. They were randomly divided into FVEP nICP monitoring group (experimental group) and the non-monitoring group (control group). The experimental group were examined lumbar puncture immediately after intracranial pressure was monitored by FVEP. Mannitol was used in reducing the elevated intracranial pressure. The serum concentrations of creatinine and urea nitrogen were recorded to assess the renal function. To evaluate the efficacy of FVEP nICP monitoring technique for clinical adjustment of mannitol. The Glasgow prognosis scores (GOS) were evaluated for patients' prognosis between two groups. Results There was no statistical significance between FVEP nICP measurement and lumbar puncture intracranial pressure measurement (195.76 ±58.88 mmH2O vs 197.04 ±53.72 mmH2O, P>0.05). Linear correlation analysis indicated that there was a strong positive relationship between the measurements (r=0.950, P<0.01). The duration prescription time and the average usage amount of mannitol in the experimental group was significantly less than that in the control group ( P < 0.05), and the serum creatinine and urea nitrogen concentrations in the two groups were not statistically significant ( P > 0.05). The cure rate of the experimental group was higher than that of the control group ( χ 2 =3.889, P =0.048). Conclusion FVEP nICP monitoring technology could replace invasive intracranial pressure monitoring technology in part HICH patients. The application of FVEP nICP technique can reduce the dosage of mannitol and improve the prognosis of patients with HICH.

Intracranial pressure monitoring

10.21203/rs.3.rs-29768/v2

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A review on colloidal delivery vehicles using carvacrol as a model bioactive compound

Food Hydrocolloids (2021)

Pu Wang Ying Wu

Carvacrol

Solid lipid nanoparticle

Microemulsion

10.1016/j.foodhyd.2021.106922

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Citations (33)

Hempseed protein (Cannabis sativa L.): Influence of extraction pH and ball milling on physicochemical and functional properties

Food Hydrocolloids (2023)

Sharath Julakanti Anto Pradeep Raja Charles Jing Zhao Fitzroy Bullock Rabia Syed

Protein purification

Zeta potential

10.1016/j.foodhyd.2023.108835

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Enhancing Sustainable Cultivation of Organic Bell Pepper through Fulvic Acid (FA) Application: Impact on Phytochemicals and Antioxidant Capacity under Open-Field Conditions

Sustainability (2024)

Pinkky Kanabar Ying Wu Dilip Nandwani

Fulvic acid (FA) is an eco-friendly solution for reducing the reliance on agrochemicals and enhancing crop quality. The study aimed to investigate the impact of soil and foliar application of FA on the phytochemical content and antioxidant properties of organically grown bell peppers at both the green and red stages. Bell pepper cv. Revolution was grown under open-field conditions at the certified organic farm at Tennessee State University, Nashville, with nine treatments and three replications. FA was applied as a soil drench and foliar spray at four different rates (0, 2.3, 5.5, 7.8, 10.9 mL L−1). The fruits were harvested 55 days (green stage) and 86 days after transplantation (red stage). The study showed significant differences (p ≤ 0.05) between the treatment and maturation stage. The foliar treatment of 7.8 mL L−1 resulted in the highest phenolic content in green bell peppers. The highest total flavonoid content in red bell peppers was achieved with a soil treatment of 7.8 mL L−1. Additionally, the highest level of vitamin C in red bell peppers occurred with a soil concentration of 5.5 mL L−1. In conclusion, applying FA as a biostimulant can enhance the quality of organically grown bell peppers, offering promising opportunities for sustainable agricultural practices.

Fulvic acid

10.3390/su16166745

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