A review on colloidal delivery vehicles using carvacrol as a model bioactive compound
33
Citation
179
Reference
10
Related Paper
Citation Trend
Keywords:
Carvacrol
Solid lipid nanoparticle
Microemulsion
In this paper,we discussed on solubilization of microemulsions composed of methyl salicylate(heptane),Tween 80(Tween 60),alcohol and water by titration. The microemulsions region and liquid crystal region were obtained by pseudo-ternary phase diagrams. We could draw a conclusion that microemulsion solubilization was effected with both the total amount of surfactant and cosurfactant on the interfacial film of microemulsion and confusable degree of interfacial film of microemulsion.
Microemulsion
Heptane
Cite
Citations (0)
HISTORICAL PERSPECTIVE Microemulsions-A Historical Overview, B. Lindman and S.E. Friberg STRUCTURAL ASPECTS AND CHARACTERIZATION OF MICROEMULSIONS Thermodynamics of Microemulsions I, W.K. Kegel, J.T.G. Overbeek, and H.N.W. Lekkerkerker Thermodynamics of Microemulsions II, E. Ruckenstein Microscopic Models of Microemulsions, G. Gompper and M. Schick Lattice Monte Carlo Simulations of Micellar and Microemulsion Systems, R. Rajagopalan, L. A. Rodriguez-Guadarrama, and S.K. Talsania Effects of Alcohol Chain Length and Salt on Phase Behavior and Critical Phenomena in SDS Microemulsions , A. M. Bellocq Aggregation Behavior in One-Phase (Winsor IV) Microemulsion Systems, S. Ezrahi, A. Aserin, and N. Garti Ionic Microemulsions, J.-L. Salager and R.E. Anton Supercritical Microemulsions, G.J. McFann and K.P. Johnston Characterization of Microemulsions by NMR, B. Lindman, U. Olsson, and O. Soderman Rheological Properties of Microemulsions, M. Gradzielski and H. Hoffmann Light Scattering Studies of Microemulsion Systems, D. Langevin and J. Rouch Characterization of Microemulsions Using Fast Freeze-Fracture and Cryo-Electron Microscopy, J.R. Bellare, M.M. Haridas, and X.J. Li Characterization of Microemulsions by Electrical Birefringence, Z.A. Schelly REACTIONS IN MICROEMULSIONS Organic Reactivity in Microemulsions, C.A. Bunton and L.S. Romsted Application of Microemulsions in Enhancing Sensitivity of Reactions in Spectroscopic Analysis, R. Guo and X. Zhu Preparation of Ultrafine Particles of Metals and Metal Borides in Microemulsions, J.B. Nagy Microemulsion-Mediated Synthesis of Nanosize Oxide Materials, K. Osseo-Asare Time-Resolved Luminescence Quenching in Microemulsions, M. Almgren and H. Mays Structure and Reactions in Microemulsions Formed in Near-Critical and Supercritical Fluids, J.L. Fulton Electrochemical Studies in Microemulsions, S. Qutubuddin Polymerization in Microemulsions, F. Candau Enzymatic Reactions in Microemulsions, K. Holmberg APPLICATIONS OF MICROEMULSIONS Applications of Microemulsions in Enhanced Oil Recovery, V. Pillai, J.R. Kanicky, and D.O. Shah Microemulsions in Pharmaceuticals, M. Malmsten Microemulsions in Cosmetics, P.A. Aikens and S.E. Friberg Microemulsions in Foods, S. Engstrom and K. Larsson Application of Microemulsions as Liquid Membranes, J.M. Wiencek Application of Microemulsions in Textile Cleaning Using Model Detergency Tests, H.-D. Dorfler FUTURE PROSPECTS The Future of Microemulsions, J. Sjoblom and S.E. Friberg
Microemulsion
Cite
Citations (700)
Overview of basic aspects of microemulsions how to prepare microemulsions - temperature-intensive microemulsions the applications of microemulsions for analytical determinations microemulsions in biotechnology microemulsions in the pharmaceutical field - perspectives and applications solubilization of drugs in microemulsions microemulsions in foods - properties and applications microemulsions in cosmetics microemulsions in agro-chemicals microemulsions in dyeing processes microemulsions as nanosize reactors for the synthesis of nanoparticles of advanced materials use of microemulsions in the production of nanostructured materials the microemulsion/gel method microemulsions in enhanced oil recovery - middle-phase microemulsion formation with some typical anionic surfactants microemulsion and optimal formulation occurence in pH-dependent systems as found in alkaline-enhanced recovery microemulsions in the chemical EOR process use of microemulsions for the extraction of contaminated soils the hole of microemulsions in detergency processes emulsions and microemulsions in metal-working processes.
Microemulsion
Cite
Citations (424)
Origanum, Satureja and Thymus genus are characterized by their thymol and carvacrol odour generally. Thymol and carvacrol containing are changed from region to region and from species to species. The essential oil of Thymbra spicata growing wild in Turkey, from three different locations were investigated by GC. 18 components were identified, the main ones being carvacrol, g-terpinene, p-cymene, thymol and caryophyllene.
Carvacrol
Thymol
Origanum
p-Cymene
Cite
Citations (5)
Carvacrol
Cite
Citations (344)
The composition change of microemulsion system in microemulsion flooding will inevitably cause the change of phase behavior. Microemulsion with different phase types directly affects its performance and displacement efficiency of microemulsion flooding. Therefore, in order to accurately describe this change, this paper, starting from the composition of microemulsion, gives the physicochemical properties characterization methods of microemulsion phase density, viscosity and interfacial tension, and simulates the change of physicochemical properties of microemulsion phase caused by microemulsion entering the high water-oil ratio zone in the process of flooding. The research results are of great significance for screening microemulsion systems and determining the displacement efficiency.
Microemulsion
Cite
Citations (1)
In vitro and in vivo studies were conducted to test a new carvacrol‐based product designed to delay the carvacrol release so that it could reach the caeca of broiler chickens in order to control Campylobacter jejuni. Antimicrobial activity of carvacrol, a constituent of oregano and thyme essential oil, has been demonstrated against C. jejuni in vitro, and this compound was found beneficial for broiler growth. Here, we tested a new liquid formulation that did not change the antibacterial efficacy of carvacrol against C. jejuni in vitro, as assessed by broth microdilution. The mode of action of carvacrol also remained unchanged as illustrated by electronic microscopy. A pharmacokinetic assay monitored carvacrol of the solid galenic formulation in the avian digestive tract and this showed that this compound was mainly found in the last part (caeca, large intestine) and in the droppings. Extremely low concentrations of free carvacrol were present in blood plasma, with larger amounts of carvacrol metabolites: carvacrol glucuronide and sulphate. A qPCR analysis showed that the solid galenic form of carvacrol added at 5 kg per tonne of food (i.e. 9·5 mg of carvacrol per kg of bodyweight per day) significantly decreased the C. jejuni caecal load by 1·5 log. The new liquid formulation was as effective as unformulated carvacrol in vitro. In vivo the solid galenic form seems to delay the carvacrol release into the caeca and presented interesting results on C. jejuni load after 35 days. Results suggested that this product could be promising to control Campylobacter contamination of broilers.
Carvacrol
Thymol
Origanum
Cite
Citations (17)
This chapter contains sections titled: Introduction Thermodynamic Definition of Microemulsions Mixed-Film and Solubilisation Theories of Microemulsions Thermodynamic Theory of Microemulsion Formation Characterisation of Microemulsions Using Scattering Techniques Characterisation of Microemulsions Using Conductivity NMR Measurements Formulation of Microemulsions References Further Reading
Microemulsion
Cite
Citations (0)
Microemulsions are compounded separately with H_2O and different concentrations of sucrose solutions as aqueous phase at mass ratio 1∶1∶2 of CTAB/1-butanol/benzene and 30 ℃.The conductivity of microemulsion with different content of aqueous phase was measured.Microemulsion region and conductivity of microemulsion with 0-0.15 mol·dm~(-3) sucrose solution are similar to microemulsion with water.Microemulsion region of microemulsion with 0.15-0.85 mol·dm~(-3) sucrose solution is similar to microemulsion with water,and the conductivity is more smaller.Microemulsion region and conductivity of microemulsion with 0.85-2 mol·dm~(-3) sucrose solution are more smaller than microemulsion with water.
Microemulsion
n-Butanol
Aqueous two-phase system
Cite
Citations (0)
Carvacrol is a component of several essential oils and has been shown to exert antimicrobial activity. The structural requirements for the activity of carvacrol were determined by comparison to structurally related (nonessential oil) compounds. Removal of the aliphatic ring substituents of carvacrol slightly decreased the antimicrobial activity. The effect of the hydroxyl group of carvacrol on activity could not be determined by simply comparing it to p-cymene, because this compound is immiscible with water; therefore, 2-amino-p-cymene, the amino analogue of carvacrol, which has a similar hydrophobicity and structural characteristics, was used. 2-Amino-p-cymene had similar membrane disruption and bacterial killing characteristics as carvacrol showing that, contrary to previous reports, the hydroxyl group of carvacrol itself is not essential for the antimicrobial activity. However, the observed 3-fold lower activity for 2-amino-p-cymene as compared to carvacrol indicates special features in the antimicrobial mode of action of carvacrol due to the hydroxyl group. Keywords: Carvacrol; essential oil; antimicrobial activity
Carvacrol
p-Cymene
Cite
Citations (267)