ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSesquiterpene Furans and Thiosesquiterpenes from the Nudibranch Ceratosoma brevicaudatumMohamad B. Ksebati and Francis J. SchmitzCite this: J. Nat. Prod. 1988, 51, 5, 857–861Publication Date (Print):September 1, 1988Publication History Published online1 July 2004Published inissue 1 September 1988https://pubs.acs.org/doi/10.1021/np50059a007https://doi.org/10.1021/np50059a007research-articleACS PublicationsRequest reuse permissionsArticle Views213Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry of coelenterates. XII. Hydroxyancepsenolide, a dilactone from the octocoral, Pterogorgia ancepsFrancis J. Schmitz, E. Donald Lorance, and Leon S. CiereszkoCite this: J. Org. Chem. 1969, 34, 6, 1989–1990Publication Date (Print):June 1, 1969Publication History Published online1 May 2002Published inissue 1 June 1969https://pubs.acs.org/doi/10.1021/jo01258a110https://doi.org/10.1021/jo01258a110research-articleACS PublicationsRequest reuse permissionsArticle Views73Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A new member of the psammaplysin family, psammaplysin F (6), has been isolated from an undescribed species of Aplysinella sponge, along with the four known psammaplysins A−C (1−3) and E (5). The structure of psammaplysin F was determined by spectral analysis.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSarasinoside A1: a saponin containing amino sugars isolated from a spongeFrancis J. Schmitz, Mohamad B. Ksebati, Sarath P. Gunasekera, and Santosh AgarwalCite this: J. Org. Chem. 1988, 53, 25, 5941–5947Publication Date (Print):December 1, 1988Publication History Published online1 May 2002Published inissue 1 December 1988https://pubs.acs.org/doi/10.1021/jo00260a025https://doi.org/10.1021/jo00260a025research-articleACS PublicationsRequest reuse permissionsArticle Views208Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of artekeiskeanol A, a newly isolated coumarin derivative from Artemisa keiskeana Miq. (Compositae), the extract of which is used for treatment of rheumatoid arthritis as a folk medicine, on the antigen-induced activation of RBL-2H3 cells were examined. RBL-2H3 cells were sensitized with dinitrophenol (DNP)-specific IgE, and then stimulated with the antigen DNP-conjugated human serum albumin (DNP‐HSA). Artekeiskeanol A at 10 to 100 µM inhibited the antigen-induced degranulation in a concentration-dependent manner, the IC50 value being 38.0 ± 0.2 µM. Degranulation induced by thapsigargin or A23187 also was inhibited by artekeiskeanol A at 10 to 100 µM. The antigen-induced increase in the levels of mRNA for tumor necrosis factor (TNF)-α and interleukin (IL)-13 and phosphorylations of Akt, p38 mitogen-activated protein kinase (MAPK), c-Jun N-terminal kinase (JNK) and p44/42 MAPK were also suppressed by artekeiskeanol A. Our findings suggested that the effectiveness of the extract of A. keiskeana might partly be due to the inhibition of mast cell activation by artekeiskeanol A.
