Montserrat Sala

Universitat Autònoma de Barcelona

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Co-Authors

Ferrán Segura

Corporació Sanitària Parc Taulí

Manuel Cervantes

Centro Español de Metrología

Bernat Font

Delft University of Technology

Ignasi Anguera

Bellvitge University Hospital

Manel Cervantes

Instituto Nacional de Perinatología

ÁU

Á Urbano-Márquez

Universitat de Barcelona

Dolors Mariscal

Corporació Sanitària Parc Taulí

María José Amengual

Hospital Universitario Son Espases

F. Segura

Hospital Privado

Bruno Frea

Azienda Ospedaliero Universitaria San Giovanni Battista

Cooperative Institutions

Instituto de Salud Carlos III

135

Centro de Investigación Biomédica en Red

113

Hospital Universitario Ramón y Cajal

Universitat Autònoma de Barcelona

Universitat de Barcelona

Corporació Sanitària Parc Taulí

Instituto Ramón y Cajal de Investigación Sanitaria

Universidad de Alcalá

Hospital General Universitario Gregorio Marañón

Hospital Clínic de Barcelona

Author Statistics

Papers

Citation

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Research Field

Micobacteriosis genitourinaria: estudio retrospectivo de 45 casos en un hospital general

Enfermedades Infecciosas y Microbiología Clínica (2008)

Marta Navarro-Vilasaró Bernat Font Montserrat Sala Antoni Prera Antoni Malet

Urination

10.1157/13128269

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Citations (20)

Disseminated Infection by Mycobacterium sherrisii and Histoplasma capsulatum in an African HIV-Infected Patient

American Journal of Tropical Medicine and Hygiene (2013)

Juan Taján Mateu Espasa Montserrat Sala M.R. Martínez Navarro Bernat Font

Mycobacterium sherrisii is a new species of opportunistic, slow-growing, non-tuberculous Mycobacterium closely related to Mycobacterium simiae that can currently be identified with the sequence of 16S rARN gene and the heat-shock protein 65. Few cases of patients infected by this Mycobacterium have been reported and all of them were associated with human immunodeficiency virus or other immunosuppressive conditions. Clinical management is complex, because there is not a clear correlation between the in vitro antibiotic susceptibility testing and the patient's clinical outcome.

Histoplasma

Opportunistic infection

AIDS-Related Opportunistic Infections

10.4269/ajtmh.12-0572

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Citations (14)

Primary HIV Type-1 Infection Misdiagnosed as Mediterranean Spotted Fever

European Journal of Clinical Microbiology & Infectious Diseases (2002)

F. Segura E. Ant x F n Bernat Font Montserrat Sala M. Cervantes

Maculopapular rash

Medical microbiology

10.1007/s10096-002-0750-0

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Citations (11)

Serosurvey of Rickettsia typhi and Rickettsia felis in HIV‐infected patients

Microbiology and Immunology (2014)

María Mercedes Nogueras Immaculada Pons Isabel Sanfeliú Montserrat Sala Ferrán Segura

Consistent with the effects of HIV on cell-mediated immunity, an increased susceptibility to intracellular microorganisms has been observed. Rickettsiae are obligate intracellular microorganisms. The aim of this study was to examine Rickettsia typhi and Rickettsia felis infections in HIV+ population. Sera of 341 HIV+ patients were evaluated by indirect immunofluorescent assay. Age, sex, residential locality, risk behavior, stage according to criteria of the Center for Disease Control and Prevention, CD4+/CD8+ T cells, Hepatitis B antigen, and Hepatitis C serology were surveyed. Seroprevalences of R. typhi and R. felis infection were 7.6% and 4.4%, respectively. No associations were found between seropositivities and the assessed variables. Findings were similar to those obtained in healthy subjects from the same region.

Rickettsia typhi

10.1111/1348-0421.12138

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Citations (11)

Efficacy and Safety of Pegylated Interferon-α2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in HIV-Infected Patients

AIDS Research and Human Retroviruses (2006)

Miguel Santín Evelyn Shaw M. Jose Garcia Antonio Delejido Eduardo Rodríguez de Castro

Low response rates and concerns about safety have limited the implementation of treatment for chronic hepatitis C (CHC) in patients with HIV infection. The efficacy and safety of pegylated interferon (peg-IFN) plus ribavirin in HIV-infected patients with CHC were evaluated in a prospective, open-label, multicenter study. Sixty patients with persistently high transaminases, positive HCV-RNA, CD4 count ≥300 cells/µl, and HIVRNA <10,000 copies/ml were included. Patients were given peg-IFN 80–150 µg/week plus ribavirin 800–1200 mg/day. Treatment was scheduled for 24 weeks for genotypes 2/3 and 48 weeks for genotypes 1/4. In an intent- to-treat analysis, 16 (26.7%) patients achieved a sustained virological response (SVR). Twenty patients (33.3%) discontinued treatment prematurely, but only in 10 (16.6%) was discontinuation due to adverse events. Negative predictive values for SVR on the basis of HCV-RNA decline between baseline and week 4 were 100% for 1- and 2-log10 fall, and positive predictive values were 40% and 58.3% for 1- and 2-log10 fall, respectively. CD4 fell by a median of 216 cells during treatment, but no HIV-associated complications occurred. In conclusion, treatment with peg-IFN alfa-2b plus ribavirin is safe and clears RNA-HCV in about one-quarter of HIV-infected patients with CHC. Efforts should be focused on optimizing management of side effects and counseling to improve adherence and to keep patients on treatment. Assessment of HCV-RNA at week 4 may help guide early therapeutic decision making.

Discontinuation

Pegylated interferon

Hepatitis C

10.1089/aid.2006.22.315

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Citations (18)

Recurrent Stroke as a Manifestation of Primary Angiitis of the Central Nervous System in a Patient Infected With Human Immunodeficiency Virus

Archives of Neurology (2002)

Carmen Nogueras Montserrat Sala M Sasal Jaume Viñas Natália Garcia

Context

Cerebral vasculitis in patients infected with human immunodeficiency virus (HIV) is usually related to additional or secondary infectious agents other than neoplastic diseases or HIV itself.

Objective

To describe a 31-year-old patient infected with HIV who presented with 2 recurrent, acute episodes of neurologic impairment in a 5-month period.

Design

Comparison of clinical and histologic data between the present case and previously published cases.

Setting

Community hospital.

Patient

A 31-year-old, HIV-infected patient with recurrent strokes and chronic lymphocytic meningitis.

Intervention

After ruling out cardiac embolisms and coagulation disorders, the presence of central nervous system vasculitis, probably secondary to an infectious process, was suspected based on the clinical examination and cerebrospinal fluid abnormalities.

Results

Necropsy findings suggest the diagnosis of primary angiitis of the central nervous system, and the only infectious agent that could be found was HIV.

Conclusions

Histologic studies were compatible with a diagnosis of primary angiitis of the central nervous system, but the pathogenic role of HIV in the genesis of the vasculitic process cannot be elucidated.

Cerebral vasculitis

Stroke

10.1001/archneur.59.3.468

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Citations (61)

[Type II essential mixed cryoglobulinemia and renal disease. Hepatitis C virus association].

PubMed (2002)

Jaume Almirall María José Amengual T. Herrero Lopez Xavier Andreu J. Oristrell

Cryoglobulins

Membranoproliferative glomerulonephritis

Microhematuria

Membranous Nephropathy

Source

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Citations (3)

On alcholic myopathy

Annals of Neurology (1985)

Á Urbano-Márquez Ramón Estruch Josep M. Grau Josep Manuel Fernández‐Huerta Montserrat Sala

General hospital

10.1002/ana.410170423

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Citations (11)

Pulmonary Nocardiosis: Clinical Experience in Ten Cases

Respiration (2001)

Bernard Mari Concepciόn Montόn Dolors Mariscal Manel Luján Montserrat Sala

Pulmonary nocardiosis is an infrequent infection whose incidence seems to be increasing due to a higher degree of clinical suspicion and the increasing number of immunosuppressive factors.To study the predisposing factors, clinical characteristics, diagnostic procedures, treatment and progress of pulmonary nocardiosis (PN).Review of 10 patients (9 male, 1 female, mean age 61) with PN in a 600-bed teaching hospital, diagnosed from 1992 to 1999.Associated diseases observed were chronic obstructive pulmonary disease (COPD) in 6 patients, human immunodeficiency virus (HIV) infection in 3 and polymyalgia rheumatica in 1. Four patients had received oral corticotherapy for COPD for over a year (mean dose 13 mg/day of prednisone or equivalent). The main reason for consultation was an increase in dyspnea in the patients with COPD (6/6) and fever in those with HIV (3/3). Mean time between onset of symptoms and diagnosis was 5 weeks. In 8 patients, the infection occurred outside the hospital setting. The infection was restricted to the lung in 9/10; in the remaining case, the central nervous system (CNS) and subcutaneous tissue were affected. Lobar or multilobar consolidation was the most frequent radiographic pattern found (6/10). Sputum culture was positive when performed (8 cases). Diagnosis was made or confirmed by bronchoscopy (bronchoaspirate or protected specimen brush) in 5 patients. Germs isolated were: Nocardia asteroides (8/10), Nocardia farcinica (1/10), Nocardia otitidiscaviarum (1/10). Cotrimoxazole was the most used empirical treatment (6/10). Resolution was achieved in 5 cases. Four subjects died: 1 HIV patient with disseminated nocardiosis, and 3 COPD patients, 2 of whom had received long-term corticotherapy. Illness recurred in only 1 case, due to failure to comply with treatment.(1) In our geographical setting Nocardia presents as a subacute or chronic pulmonary infection, mainly outside the hospital. (2) It tends to affect only the lung. (3) Diagnosis requires a high clinical suspicion, and can be made on the basis of a sputum culture. (4) Nocardia tends to attack patients with underlying COPD, or immunodepressed patients treated with glucocorticoids, or patients with HIV infection. (5) Mortality is high in both COPD and HIV patients. (6) In our area, cotrimoxazole seems to be the most commonly prescribed treatment.

Nocardia Infections

10.1159/000050531

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Citations (88)

1138 PRETREATMENT VIRAL GENETIC FACTORS IMPROVE IL28B PREDICTIONS OF VIROLOGIC RESPONSE TO STANDARD THERAPY IN HEPATITIS C VIRUS 1B INFECTED PATIENTS

Journal of Hepatology (2012)

Verónica Saludes E. Bascuàana Mercé Ardévol Verónica González‐Calle Ramón Planas

10.1016/s0168-8278(12)61149-0

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Citations (0)