Purpose: To perform a prospective comparative analysis of lipid profiles, markers for inflammation and endothelial dysfunction in groups of coronary artery disease (CAD) patients with and without episodes of unstable coronary blood flow after percutaneous coronary intervention (PCI); and to detect factors which may be used as predictors of cardiovascular complications. Methods: A total of 95 patients aged 60.47±9.54 years with CAD and stable angina were divided into two groups. Group 1 included patients with CAD without episodes of unstable coronary blood flow after PCI (n=77) and group 2 included CAD patients with episodes of unstable coronary blood flow after PCI (n=18). All patients were matched by age, CAD duration, diabetes mellitus, blood pressure levels and smoking history. Results: Laboratory tests were performed before PCI and 12±2.4 month after. The level of lipoprotein (a), HDLC, FNO-a equally decreased in both groups. In patients of group 2 compared to group 1 there were observed significantly increased levels of atherogenic indices of the lipid profile (total cholesterol, LDL) and inflammation markers: high-sensitivity C-reactive protein, homocysteine, levels of soluble CD40 ligand (CD40L), interleukin-1β interleukin- B6, and decreased levels of nitrites. Significant correlations of inflammatory markers and endothelial dysfunction with body-weight index, family history of CAD, significant multivessel stenosis, number of angina attacks per week and presence of diabetes mellitus were revealed in group 2. Multivariate logistic regression analysis revealed that patients with unstable angina at baseline had the risk of unstable coronary blood flow after PCI 4 times higher (p=0.02). Conclusion: The inflammatory markers: C-reactive protein, homocysteine, CD40L can initiate unstable coronary blood flow after coronary angioplasty and stenting.

Unstable angina

Endothelial Dysfunction

Lipid Profile

10.1093/cvr/cvu098.145

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[Prevalence and intensity of smoking among adult urban population of Tiumen': data of population mail questionnaire survey].

PubMed (2000)

Akimova Ev В. В. Гафаров Dracheva Lv Kuznetsov Va

To estimate prevalence and intensity of smoking among adult Tyumen citizens by mail questionnaire survey.A representative sample of adult population of Tyumen (central district) was randomly selected using the list of the electors. The questioning covered a total of 3200 citizens (8 groups per 400 age- and sex-matched subjects). The response reached 71.5%. Smoking in the population was studied in three aspects: prevalence, intensity and passive smoking.Overall prevalence of smoking was not great (28.8%), but smoking was frequent in women, especially young, was intensive in males of all the age groups. The number of smokers who had quit smoking was small. Passive smoking at jobs was prevalent.The data of the survey indicate difficulties of social adaptation for the studied population who fall under risk to develop cardiovascular diseases.

Questionnaire

Smoking prevalence

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Hall Effect in Strong Electric Fields in AlGaAs/InGaAs/GaAs Heterostructures with Donor-Acceptor Doping

Kuznetsov Va D. Yu. Protasov V. Ya. Kostyuchenko Karl K. Sabelfeld Е. Г. Каблукова

This article presents theoretical and experimental dependences of the Hall voltage in high electric fields with a static magnetic field. Measurements were carried out on the pHEMT heterostructure with donor-acceptor doping. Due to the fact that in high electric fields there is a distribution of electrons from the $\Gamma$ -valley to the satellite L-and X-valleys, it is expected that the dependence of the Hall voltage on the electric field will be nonlinear. The Hall voltage was modeled for fields up to 10 kV/cm. Theoretical calculations predict saturation at the electric field of about 3.5 kV/cm, and then a decrease in the Hall voltage at large fields. Experimentally, it was possible to measure only up to the moment of saturation. However, saturation in the experiment occurred earlier than in the theoretical model (with the electric field of about 1 kV/cm). Assumptions have been made as to what this may be due to.

Saturation (graph theory)

Acceptor

10.1109/edm58354.2023.10225239

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Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology (2018)

Georgiy Pushkarev Kuznetsov Va Yakov A Fisher А. М. Солдатова T. N. Enina

10.5543/tkda.2018.38834

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916 Aortic elastance and coronary atherosclerosis

European Journal of Echocardiography (2005)

Kuznetsov Va Svetlana Vdovenko Д. В. Криночкин Elena Doniy И. П. Зырянов

Coronary atherosclerosis

Elastance

10.1016/s1525-2167(05)80526-8

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LEFT MAIN CORONARY ARTERY DISEASE: CURRENT STATUS AND MANAGEMENT

The Siberian Journal of Clinical and Experimental Medicine (2017)

И. С. Бессонов Kuznetsov Va

The review article describes the current trends in the treatment of coronary artery disease (CAD) in patients with left main coronary artery stenosis (LMCA). The article shows the clinical and morphological characteristics of CAD in patients with LMCA stenosis, and describes the benefits of revascularization. Safety and efficacy of percutaneous coronary intervention versus coronary bypass surgery grafting were analyzed using up-to-date evidence base.

10.29001/2073-8552-2017-32-3-14-21

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ФЕНОМЕН ИШЕМИЧЕСКОГО ПРЕКОНДИЦИОНИРОВАНИЯ МИОКАРДА,ЖЕЛУДОЧКОВАЯ ЭКСТРАСИСТОЛИЯ И ДИСПЕРСИЯ ИНТЕРВАЛА QT: ОЦЕНКА МЕТОДОМ ПАРНЫХ ТРЕДМИЛ-ТЕСТОВ

Journal of Arrhythmology (2005)

В В Тодосийчук Kuznetsov Va О Ю Нохрина Елена Александровна Лыкасова Ю А Лаптева

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“Distressed” personality in patients with coronary artery disease after percutaneous coronary intervention

Atherosclerosis (2015)

Kuznetsov Va Г. С. Пушкарев E. I. Yaroslavskaya Д. В. Криночкин И. С. Бессонов