Nikos K. Logothetis

Chinese Academy of Sciences

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Christoph Kayser

Bielefeld University

Stefano Panzeri

University Medical Center Hamburg-Eppendorf

M Augath

Institute for Biomedical Engineering

Georgios A. Keliris

Foundation for Research and Technology Hellas

Yusuke Murayama

Kitasato University

Goran Angelovski

Chinese Academy of Sciences

O Eschenko

Max Planck Institute for Biological Cybernetics

David A. Leopold

National Institute of Neurological Disorders and Stroke

Michel Besserve

Max Planck Institute for Biological Cybernetics

Christopher I. Petkov

Newcastle University

Cooperative Institutions

Max Planck Institute for Biological Cybernetics

243

Max Planck Society

231

University of Surrey

168

Instituto de Ciencias Agrarias

151

Chinese Academy of Sciences

115

University College London

University of Tübingen

University of Cambridge

History of Science Society

Centre National de la Recherche Scientifique

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Modelling Spikes with Mixtures of Factor Analysers

Lecture notes in computer science (2004)

Dilan Görür Carl Edward Rasmussen Andreas S. Tolias Fabian H. Sinz Nikos K. Logothetis

Spike sorting

Generative model

Factor (programming language)

10.1007/978-3-540-28649-3_48

Cite

Citations (11)

Editorial Board

Trends in Cognitive Sciences (2011)

Stavroula Kousta Katja Brose Rolf Van Der Sanden Patrick Scheffmann Ria Otten

Editorial board

10.1016/s1364-6613(11)00161-6

Cite

Citations (0)

Off‐line quality control and ill‐designed data

Quality and Reliability Engineering International (1987)

Nikos K. Logothetis

Abstract ‘Bad’ data resulting from ill‐designed experiments or in‐production/after‐production monitoring require a careful use of proper statistical techniques for their analysis. Prior exploration of the available data is of paramout importance especially if we wish to apply off‐line quality control techniques such as the Taguchi method. A stepwise approach is proposed involving data analysis and straightforward significance tests, which can ensure statistically valid and useful conclusions.

Statistical Process Control

Production line

Line (geometry)

10.1002/qre.4680030405

Cite

Citations (5)

Research articles Anatomical and functional MR imaging in the macaque monkey using a vertical large-bore 7 Tesla setup

Josef Pfeuffer Hellmut Merkle Michael Beyerlein T Steudel Nikos K. Logothetis

Functional magnetic resonance imaging (MRI) in the nonhuman primate promises to provide a much desired link between brain research in humans and the large body of systems neuroscience work in animals. We present here a novel high field, large-bore, vertical MR system (7 T/60 cm, 300 MHz), which was optimized for neuroscientific research in macaque monkeys. A strong magnetic field was applied to increase sensitivity and spatial resolution for both MRI and spectroscopy. Anatomical imaging with voxel sizes as small as 75150300 Am 3 and with high contrast-to-noise ratios permitted the visualization of the characteristic lamination of some neocortical areas, e.g., Baillarger lines. Relaxation times were determined for different structures: at 7 T, T1 was 2.01/1.84/1.54 s in GM/GM-V1/ WM, T2 was 59.1/54.4 ms in GM/WM and T2* was 29 ms. At 4.7 T, T1 was 25% shorter, T2 and T2* 18% longer compared to 7T. Spatiotemporally resolved blood-oxygen-level-dependent (BOLD) signal changes yielded robust activations and deactivations (negative BOLD), with average amplitudes of 4.1% and 2.4%, respectively. Finally, the first high-resolution (500 Am in-plane) images of cerebral blood flow in the anesthetized monkey are presented. On functional activation we observed flow increases of up to 38% (59 to 81 ml/100 g/min) in the primary visual cortex, V1. Compared to BOLD maps, functional CBF maps were found to be localized entirely within the gray matter, providing unequivocal evidence for high spatial specificity. The exquisite sensitivity of the system and the increased specificity of the hemodynamic signals promise further insights into the relationship of the latter to the underlying physiological activity.

Blood-oxygen-level dependent

Non human primate

Source

Cite

Citations (0)

Attentional Enhancement Opposite a Peripheral Flash Revealed Using Change Blindness

Psychological Science (2003)

Peter U. Tse DL Sheinberg Nikos K. Logothetis

We describe a new method for mapping spatial attention that reveals a pooling of attention in the hemifield opposite a peripheral flash. Our method exploits the fact that a brief full-field blank can interfere with the detection of changes in a scene that occur during the blank. Attending to the location of a change, however, can overcome this change blindness, so that changes are detected. The likelihood of detecting a new element in a scene therefore provides a measure of the occurrence of attention at that element's location. Using this measure, we mapped how attention changes in response to a task-irrelevant peripheral cue. Under conditions of visual fixation, change detection was above chance across the entire visual area tested. In addition, a "hot spot" of attention (corresponding to near-perfect change detection) elongated along the cue-fixation axis, such that performance improved not only at the cued location but also in the opposite hemifield.

Cued speech

Change blindness

Blank

Peripheral vision

Pooling

10.1111/1467-9280.t01-1-01425

Cite

Citations (50)

A smart ¹⁹F and ¹H MRI probe with self‐immolative linker as a versatile tool for detection of enzymes

Contrast Media & Molecular Imaging (2012)

A Keliris Ilgar Mamedov G Hagberg Nikos K. Logothetis Klaus Scheffler

ABSTRACT Here we report on a dual‐modal 19 F and 1 H MRI paramagnetic probe with a self‐immolative linker, Gd–DOMF–Gal. The enzymatic conversion of this probe by β ‐galactosidase resulted in a simultaneous turning on of the fluorine signal and changed ability of the Gd 3+ complex to modulate the 1 H MR signal intensity of the surrounding water molecules. A versatile imaging platform for monitoring a variety of enzymes by 19 F and 1 H MRI using this molecular design is proposed. Copyright © 2012 John Wiley & Sons, Ltd.

Linker

10.1002/cmmi.1470

Cite

Citations (40)

Flat map areal topography in Macaca mulatta based on combined MRI and histology

Magnetic Resonance Imaging (2010)

Fahad Sultan Salah Hamodeh Yusuke Murayama Kadharbatcha S. Saleem Nikos K. Logothetis

Neocortex

Histology

Brain atlas

Representation

Brain mapping