Kıvanç Bektaş Kayhan

Istanbul University

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MÜ

Meral Ünür

Istanbul University

Gizem Karagöz

Dicle University

Ceren Damla Özbek

Istanbul University

İÖ

İlknur Özcan

Biruni University

Musa Altun

Istanbul University

BÇ

Bedia Çakmakoğlu

Istanbul University

Günter Hafız

Istanbul University

Yaren Keskin

Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi

Zeynep Boy Metin

University of Dental Medicine

Ahmet Karadeniz

Istanbul University

Cooperative Institutions

Istanbul University

115

Sağlık Bilimleri Üniversitesi

Ministry of Health

Hacettepe University

Başkent University

University of Adelaide

Kocaeli Üniversitesi

Istanbul University-Cerrahpaşa

Universidade de São Paulo

Ankara University

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Systematic review of antimicrobials, mucosal coating agents, anesthetics, and analgesics for the management of oral mucositis in cancer patients and clinical practice guidelines

Supportive Care in Cancer (2020)

Deborah Saunders Tanya Rouleau Karis Kin Fong Cheng Noam Yarom Abhishek Kandwal

Mucositis

Guideline

Pain medicine

Sucralfate

Evidence-Based Practice

10.1007/s00520-019-05181-6

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Citations (65)

Post-radiotherapy dental screening: overview of 104 head-neck cancer patients

Kıvanç Bektaş Kayhan G. Karagoz Cengiz Özbek S. Altop Mümtaz Cem Şirin

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BAŞ-BOYUN KANSERLERİNDE TEDAVİ ÖNCESİ DENTAL GİRİŞİMLER:Dental Assessment of Patients with Head-Neck Cancer Prior to Anticancer Therapy: Review of 35 Cases

Journal of İstanbul university faculty of dentistry/Journal of Istanbul University faculty of dentistry (2012)

Kıvanç Bektaş Kayhan Meltem Özdemir Karataş Meral Ünür Yaren Keskin Musa Altun

OZ Amac: Bas-boyun kanserlerinin tedavisinde uygulanan cerrahi, radyoterapi ve kemoterapi sonucunda tat almada bozukluk, mukozit, agiz kurulugu, radyasyon curukleri, Gerec ve Yontem: Bu calismada Ekim 2006-Kasim 2007 tarihleri arasinda klinigimize agiz dis sagligi konsultasyonu icin basvuran 35 Bulgular: Hastalarin onkoloji tedavisine Sonuc: Onkoloji tedavisine baslamadan once yapilacak Anahtar kelimeler: Bas-boyun kanserleri, kemo-radyoterapi, trismus, yara iyilesmesinde gecikme ve osteoradyonekroz gibi yan etkiler olusabilmektedir. Calismamizin amaci, bu yan etkilerin onlenmesi ve/veya en aza indirilmesi icin hastalarin, tedavi oncesi ve sonrasi durumlarini karsilastirmak ve dental degerlendirmenin onemini vurgulamaktir. primer bas-boyun kanseri hastasinin degerlendirilmesi, uygulanan tedaviler ve ortalama 16,9 aylik takiplerinin sonuclari bildirilmistir. dental olarak hazirlanmalari icin tum hastalara periodontal olarak baslangic tedavisi yapilmistir. Ayrica 9 hastanin toplam 28 disine konservatif restorasyonlar yapilirken, 9 hastaya sabit protez, 13 hastaya da hareketli protez uygulamalari yapilmistir. dental hazirliklar, tedavi esnasinda ve sonrasinda devam edecek duzenli kontroller, hastalarin tedavi sonrasindaki donemde agiz ve dis sagligi yonunden yasayacaklari problemleri en aza indirecek ve hayat kalitelerini arttiracaktir. dental degerlendirme, oral komplikasyonlar ABSTRACT Purpose: Head and neck cancer therapy including surgery, radiotherapy and chemotherapy may lead to acute and chronic complications of such as alterations in taste, oral mucositis, hyposalivation, radiation induced dental caries, trismus, delayed wound healing and osteoradionecrosis. The aim of our study is to compare the oral situation of patients, before and after treatment and emphasize the importance of the dental evaluation due to prevent and / or minimize of these complications. 35 patients with primary head and neck tumors who had applied to our clinic between October 2006 and November 2007 for the oral health care consultation, dental treatments, and the 16,9-month follow-up results were reported. 28 teeth of 9 patients, fixed dentures in 9 patients, moving prosthetic applications in 13 patients were performed. Conclusion: Dental arrangements to do before oncology treatment, ongoing regular follow-up during and after treatment will minimize the problems of oral health after cancer treatment and increase quality of life. Keywords: Head-neck cancers, chemo-radiotherapy, dental evaluation, oral complications

Trismus

Osteoradionecrosis

Mucositis

10.17096/jiufd.11006

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An Extreme Case of Brown Tumor Affecting Both Jaws

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology (2015)

Kıvanç Bektaş Kayhan Ferihan Aral Nihan Aksakallı Meral Ünür

Brown tumor

Mandible (arthropod mouthpart)

Osteitis fibrosa cystica

10.1016/j.oooo.2014.07.164

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Does lower dose pilocarpine have a role in radiation-induced xerostomia in the modern radiotherapy era? A single-center experience based on patient-reported outcome measures

European Archives of Oto-Rhino-Laryngology (2024)

Dilek Gül Beste M. Atasoy Ece Ercan Zilan Başkan Kıvanç Bektaş Kayhan

Abstract Purpose This study aims to investigate the efficacy of lower dose pilocarpine in alleviating late dry mouth symptoms in head and neck cancer patients received radiotherapy. Methods Eighteen head and neck cancer patients experiencing persistent dry mouth were enrolled in this study. All participants started pilocarpine treatment a median of 6 months post-radiotherapy. Initially, patients received pilocarpine at 5 mg/day, with a gradual increase to the recommended dose of 15 mg/day. A Patient-Reported Outcome Measurement (PROMs) questionnaire assessed symptoms’ severity related to hyposalivation. Results All patients reported symptomatic dry mouth above grade 2 before starting the medication. Pilocarpine treatment continued based on patients’ self-assessment, with a median duration of 12 months (range, 3–36 months). The median daily maintenance dose was 10 mg (range, 5 to 20 mg). Total PROMs scores significantly decreased following medication, from 13 points (range 7–18 points) to 7 points (range 4–13 points) ( p = 0.001). Significant improvements were observed in questions related to dry mouth ( p < 0.001), water intake during eating ( p = 0.01), carrying water ( p = 0.01), taste ( p < 0.001), and water intake during speech ( p < 0.001). Initial and maintenance doses of pilocarpine were lower, and the duration of pilocarpine usage was shorter in patients treated with intensity-modulated radiation therapy compared to conformal radiotherapy (12 months vs. 25 months, p = 0.04). Conclusion Pilocarpine may be considered at doses lower for late-term dry mouth. With modern radiotherapy techniques effectively preserving the parotid gland, short-term use may be recommended in these patients. Future studies may enhance the development of a more robust patient selection criteria model.

Pilocarpine

Dry mouth

10.1007/s00405-024-08616-x

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An Alternative Classification Scheme for Accessory Mental Foramen

Current Medical Imaging Formerly Current Medical Imaging Reviews (2020)

Turgut Yağmur Yalçın Kıvanç Bektaş Kayhan Ayça Yılmaz İlknur Özcan

The mental foramen (MF) is an important anatomical landmark on the mandible. MFs may occur singly or with extra foramina (accessory mental foramen (AMF)).The aim of the present study was to discuss the importance of recognition and classification of AMFs.This study assessed CBCT images of 593 patients (208 male, 385 female) and proposed an AMF classification scheme based on three different characteristics: (1) location of the AMF with respect to the MF; (2) relationship of AMFs with tooth apices; and (3) origin of the AMF. The chi-squared test was used to compare the qualitative data as well as descriptive statistical methods when the study data were evaluated. Significance was assessed at the p < 0.05 level.A total of 80 AMFs were found in 71 patients. Six cases involved bilateral AMFs, whereas three cases showed double AMFs. The most common AMF location was the region posterior of the MF. Notably, all the AMFs detected in line with the mesial half of the first molar were present in female patients. Based on AMF origins, 44.5%, 48.6%, and 6.7% of the AMFs were categorized as type I, type II, and a new category identified in this study, type III.This study revealed that some foramina locations were not considered in the previous classification. Recognition and identification of these foramina might be critical to prevent possible complications. The proposed classification scheme may facilitate this objective and can be a new focus for future studies.

Mental foramen

Anatomical landmark

Foramen

Classification scheme

10.2174/1573405616666200928143014

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Citations (4)

The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries

Gerodontology (2011)

Onur Geçkili Kıvanç Bektaş Kayhan Pınar Eren Tayfun Bilgin Meral Ünür

doi: 10.1111/j.1741‐2358.2011.00549.x The efficacy of a topical gel with triester glycerol oxide in denture‐related mucosal injuries Objective: The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel. Materials and methods: Fifty edentulous patients were enrolled in this double‐blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7 days after denture placement. Twenty‐five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel’s taste, smell and ease of use. Results: Specifically, there was no statistically significant difference in ulcer healing ( p > 0.05), ratings of smell, taste and ease of use ( p > 0.05) or pain and discomfort scores ( p > 0.05). However, within‐group differences were observed in pain and discomfort scores between follow‐up sessions ( p = 0.01 for all comparisons). Conclusion: Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.

10.1111/j.1741-2358.2011.00549.x

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ORAL LİKEN PLANUS: DİRENÇLİ BİR OLGUNUN TEDAVİSİ* Oral Lichen Planus: Treatment of a Refractory Case (Case Report)

Journal of İstanbul university faculty of dentistry/Journal of Istanbul University faculty of dentistry (2014)

Özge Özdal Ceren Damla Özbek Kıvanç Bektaş Kayhan Nesimi Büyükbabanı Meral Ünür

Oral lichen planus (OLP) is a relatively common, chronic inflammatory disease that often affects the stratified squamous epithelia of oral mucosa. The disease is affecting approximately 1-2% of the population. It is seen mostly in the third to sixth decades of life, and is twice as common in women than men. OLP’s pathogenesis of immune system is thought to have played a role in the etiology is not known. A 25-year-old male patient was referred our clinic due to white lesions on his lower lip. Similar lesions were detected on his tongue, retromolar region, gingiva as well as various parts of oral mucosa result of clinical examiation. Biopsies were taken for direct immunofluorescense (DIF) and histopathological examinations. As a result of bipsies OLP were diagnosed. In this paper the treatment of our patient and the clinical changes of patient with the treatment will be presented.

Oral Lichen Planus

Oral mucosa

Etiology

Refractory (planetary science)

10.17096/jiufd.34308

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COMPARISON OF THE TOOTH BRUSHING HABITS OF PRIMARY SCHOOL AGE CHILDREN AND THEIR PARENTS

Journal of İstanbul university faculty of dentistry/Journal of Istanbul University faculty of dentistry (2015)

Ceren Damla Özbek Didem Eser Kıvanç Bektaş Kayhan Meral Ünür

Purpose: As they grow, children develop their attitude and behavior related to tooth brushing by taking their parents' oral-dental health behavior as an example. The purpose of this study was to assess whether there was a similarity in tooth brushing between primary school-age children and their parents presenting to the Department of Oral, Dental and Jaw Diseases and Surgery and the Department of Pedodontics, School of Dental Medicine, Istanbul University. Patients and Methods: The study included 126 children and their parents, as totally 252 subjects. The data on oral hygiene of the subjects were obtained using a questionnaire form including questions on the qualitative-quantitative tooth brushing habits of the children and their parents and the socio-demographic characteristics of their families. Results: In most of the cases, there was a similarity between children and their parents in terms of the frequency of dentist visits, the therapy they underwent in their last dentist visit, the cause of caries, the frequency of tooth brushing, the material used for oral hygiene, the duration of tooth brushing, method of tooth brushing, and tooth sites most brushed, which showed a significant association between children and their parents (p<0.01). Conclusion: Correct knowledge given to the children by their families will positively affect the oral-dental health of the children. Thus, firstly, correct knowledge should be given to the parents so that they can successfully carry out their responsibility in being the correct model for their children in oral-dental health.

Tooth brushing

10.17096/jiufd.19356

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Citations (15)

A Retrospective Study on Patients with Orofacial Pain

Journal of Oral and Maxillofacial Surgery (2018)

Kıvanç Bektaş Kayhan Fatih Selvi Mustafa Özdemir Gül Köknel Talu

Orofacial Pain

Etiology

10.1016/j.joms.2018.06.139

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