Luca Bucchini

FIT Consulting (Italy)

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Jonathan Bisson

University of Illinois Chicago

Stefan Gafner

Botanical Society of America

Antonella Guzzon

University of Rome Tor Vergata

Guido F. Pauli

University of Illinois Chicago

Patrizia Restani

University of Milan

James B. McAlpine

University of Illinois Chicago

Shao‐Nong Chen

University of Illinois Chicago

J. Brent Friesen

University of Illinois Chicago

Seon Beom Kim

Pusan National University

David C. Lankin

University of Illinois Chicago

Cooperative Institutions

Barcelona Institute for Global Health

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública

Pompeu Fabra University

Instituto de Salud Carlos III

Imperial College London

Wageningen University & Research

Food & Nutrition

University of Manchester

Center for Research in Environmental Epidemiology

Norwegian Institute of Public Health

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EURRECA nutritional planning and dietary assessment software tool: NutPlan

European Journal of Clinical Nutrition (2010)

Mirjana Gurinović Agneš Kadvan Luca Bucchini Christophe Matthys Duarte Torres

Excellence

Glossary

10.1038/ejcn.2010.59

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Citations (12)

Starlink corn: a risk analysis.

Environmental Health Perspectives (2002)

Luca Bucchini Lynn R. Goldman

Modern biotechnology has dramatically increased our ability to alter the agronomic traits of plants. Among the novel traits that biotechnology has made available, an important group includes Bacillus thuringiensis-derived insect resistance. This technology has been applied to potatoes, cotton, and corn. Benefits of Bt crops, and biotechnology generally, can be realized only if risks are assessed and managed properly. The case of Starlink corn, a plant modified with a gene that encodes the Bt protein Cry9c, was a severe test of U.S. regulatory agencies. The U.S. Environmental Protection Agency had restricted its use to animal feed due to concern about the potential for allergenicity. However, Starlink corn was later found throughout the human food supply, resulting in food recalls by the Food and Drug Administration and significant disruption of the food supply. Here we examine the regulatory history of Starlink, the assessment framework employed by the U.S. government, assumptions and information gaps, and the key elements of government efforts to manage the product. We explore the impacts on regulations, science, and society and conclude that only significant advances in our understanding of food allergies and improvements in monitoring and enforcement will avoid similar events in the future. Specifically, we need to develop a stronger fundamental basis for predicting allergic sensitization and reactions if novel proteins are to be introduced in this fashion. Mechanisms are needed to assure that worker and community aeroallergen risks are considered. Requirements are needed for the development of valid assays so that enforcement and post market surveillance activities can be conducted.

Bacillus thuringiensis

Agricultural Biotechnology

Regulatory Science

10.1289/ehp.021105

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Citations (113)

RISK MANAGEMENT FOR FOOD ALLERGENS IN CEREALS AND DERIVATIVES

I. Crăciun E. Ignat A. Mărculescu Mihaela Badea L. Gaceu

The present paper discusses about food allergy with particular attention to hazard identification and risk assessment of cereals allergy. To perform a risk characterization it is important to know the threshold level for clinical reactions. If threshold is not established, the risk assessment and management is difficult and labeling such as “May contain gluten” is unavoidable even if it can be used with or without reason. Unjustified warning declarations do not help the allergic individuals but create more confusion than guidance.

Confusion

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The PlantLIBRA Project: how we intend to innovate the science of botanicals

Food & Function (2011)

Luca Bucchini Alejandro I. Rodarte Patrizia Restani

The main aim of the EC-financed R&D project PlantLIBRA (PLANT food supplements: Levels of Intake, Benefit and Risk Assessment) is to foster the safe use of food supplements containing plants or botanical preparations, by enabling science-based decision making by regulators and stakeholders. To make informed decisions, competent authorities and industry need more accessible and quality-assured information, as well as better tools (e.g., databases) and procedures for safety and benefit assessments, supported by broadly accepted methodologies. Consequently, PlantLIBRA is working to develop, validate and disseminate data and methodologies for risk and benefit assessment of plant food supplements, and to implement sustainable international cooperation. International cooperation will help ensure the quality of botanicals imported in the EU. Moreover, the project will provide data on intake by conducting a harmonized consumption survey. Existing composition and safety data will be collated into a meta-database. New analytical data and methods will be investigated and validated. The consortium is working closely with competent authorities and stakeholders.

10.1039/c1fo10150a

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Citations (8)

Maize pollen mediated gene flow in the Po valley (Italy): Source–recipient distance and effect of flowering time

European Journal of Agronomy (2007)

Giovanni Della Porta Davide Ederle Luca Bucchini M. Prandi A. Verderio

Pollen source

10.1016/j.eja.2007.07.009

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Citations (89)

Are food recalls risk based food safety tools?

Luca Bucchini L. Caricchio

10.3920/9789086865833_023

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EURRECA: development of tools to improve the alignment of micronutrient recommendations

European Journal of Clinical Nutrition (2010)

Christophe Matthys Luca Bucchini Maria C. Busstra Adriënne E.J.M. Cavelaars Polyvios Eleftheriou

Excellence

Benchmarking

Best practice

10.1038/ejcn.2010.206

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Citations (11)

A Snapshot of Federal Research on Food Allergy IMPLICATIONS FOR GENETICALLY MODIFIED FOOD

Luca Bucchini Lynn R. Goldman

6 Introduction 7 Food Allergy Impact on Health 7 Food Allergy Research Needs 9 Data Sources 11 Findings 13 Federal Support Is Limited 13 Research Is Spread Thin with Little Coordination 13 Research Will Not Address Needs for Biotechnology Regulation 15 Conclusions and Recommendations 16 Appendix I – Methods 18 Definitions 18 Data Sources 18 Types of Research 19 Appendix II – Results 22 Research Funded by Federal Agency 22 Analysis of Research 30 References 35

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How we will produce the evidence-based EURRECA toolkit to support nutrition and food policy

European Journal of Nutrition (2008)

Margaret Ashwell Janet Lambert Martine S. Alles Francesco Branca Luca Bucchini

Excellence

European commission

10.1007/s00394-008-1002-6

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Citations (58)

ePlantLIBRA: A composition and biological activity database for bioactive compounds in plant food supplements