An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that may selectively deposit two deadly high-energy particles (4He and 7Li) within a cancer cell. As a radiotherapy induced by localized nuclear reaction, few studies have reported its abscopal anti-tumour effect, which has limited its further clinical applications. Here, we engineer a neutron-activated boron capsule that synergizes BNCT and controlled immune adjuvants release to provoke a potent anti-tumour immune response. This study demonstrates that boron neutron capture nuclear reaction forms considerable defects in boron capsule that augments the drug release. The following single-cell sequencing unveils the fact and mechanism that BNCT heats anti-tumour immunity. In female mice tumour models, BNCT and the controlled drug release triggered by localized nuclear reaction causes nearly complete regression of both primary and distant tumour grafts.
Abstract Perovskites Ba 1−x K x Bi 0.30 Pb 0.70 O 3−δ (0.0 ≤ x ≤ 0.25) have been synthesized under 660 °C. P1 space group can describe well the structure of this solid solution. The valences are +3 and +5 for bismuth, +2 and +4 for lead in these compounds. The T c zer ° (the highest temperature at which the sample shows zero electrical resistivity) of Ba 1−x K x Bi 0.30 Pb 0.70 O 3−δ first increases from 8.2 K for x=0.02 to 11.4 K for x=0.15, then decreases about to 10.4 K for x=0.25.
Two-dimensional zeolitic materials have drawn increasing attention because of their structural diversity, high accessible surface areas, and potential as precursors to form novel three-dimensional (3D) structures. Here we report a new layered fluoroaluminophosphate, denoted as EMM-9 (ExxonMobil Material #9), synthesized in the same synthesis system as that for a previously reported 3D framework structure EMM-8 (framework-type code: SFO) using an F– medium and 4-(dimethylamino)pyridine (DMAP) as the organic structure-directing agent. The structure of EMM-9 was solved from rotation electron diffraction data and refined against synchrotron powder X-ray diffraction data. The fluoroaluminophosphate layer of EMM-9 is composed of sti composite building units. The DMAP cations are located between the layers. π–π interactions between the DMAP cations and hydrogen bonding between the DMAP cations and layers were identified. The layered EMM-9 structure is closely related to the 3D framework structure of EMM-8 and can be transformed to EMM-8 by calcination.
Rechargeable aqueous Zn-MnO2 batteries are promising candidates for large-scale energy storage systems, yet still plagued by the phase transition and structural collapse issues of MnO2 cathodes during cycling. Interlayer intercalation for the layered MnO2 turns out to be a viable alternative and become the mainstream structure design strategy. However, the characteristics of Mn octahedral layers are generally neglected. Herein, for the first time we elucidate apart from interlayer ions, how layer symmetry of birnessites exerts on the electrochemical performance. The Mn(II) ions stabilized hexagonal birnessite exhibits elevated charge storage performance than its monoclinic precursor, attributing to the layer cation vacancies generated after symmetry transformation, interlayer Mn(II) ions and nanosized morphology. A high specific capacity of 279 mAh g−1 at 1 C is achieved, as well as an outstanding long-term cycling stability with 97% retention over 8000 cycles. The reaction mechanism is comprehensively illustrated. This work previews a new gateway for the design of high-performance layered cathode materials by synergistic manipulation of the crystal structure of the layers and the interlayer environment.
Abstract Incorporation of water into mantle compositions can have significant effects on the phase relations in the systems. In this study, we synthesized an iron‐rich hexagonal hydrous phase (referred to as “HH1‐phase”) under the high pressure‐temperature ( P ‐ T ) conditions of the deep lower mantle and determined the crystal structure of the HH1‐phase at 79 GPa using the multigrain crystallography method. The chemical formula obtained was Fe 12.76 O 18 H x ( x ∼ 4.5) in the Fe‐O‐H system. To demonstrate the role of HH1‐phase for water storage in multicomponent systems relevant to mantle compositions, we investigated the stability of HH1‐phase in both MgO‐rich pyrolitic and SiO 2 ‐rich basaltic compositions. Our results indicate that the HH1‐phase serves as major water storage in a pyrolitic composition, whereas the Al‐rich CaCl 2 ‐type δ‐phase and SiO 2 phase are major water storage phases in a SiO 2 ‐rich basaltic composition. Incorporation of considerable amounts of SiO 2 , MgO, and Al 2 O 3 into the HH1‐phase expands its stability field from 98 GPa in the Fe‐Al‐O‐H system to at least 108 GPa (corresponding to ∼2,400 km depth) in the Mg‐Si‐Al‐Fe‐O‐H system. Plumes of hot upwelling rock rooted at the base of the lower mantle have been proposed as a possible origin of hotspot volcanoes. The hydrous Fe‐rich HH1‐phase, if included into the material of upwelling plumes, will decompose on its rising to the upper part of the lower mantle and release water. Our results should provide constraints on water storage in the deep lower mantle and have implications for deep mantle dynamics.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
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