Lin Jiang

Chongqing Medical University

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Yong Tang

Chengdu University of Traditional Chinese Medicine

Feng‐lei Chao

Chongqing Medical University

Chunni Zhou

Chongqing Medical University

Yanmin Luo

Chongqing Medical University

Xin Liang

Guangxi Buffalo Research Institute

Jing Tang

Chongqing Medical University

Qian Xiao

Chongqing Medical University

Fei Sun

Michigan State University

Chunxia Huang

Shandong First Medical University

Peilin Zhu

Chongqing Medical University

Cooperative Institutions

Chongqing Medical University

120

Chinese Academy of Sciences

Huazhong University of Science and Technology

Shanghai Jiao Tong University

Peking University

Sun Yat-sen University

Chinese Academy of Medical Sciences & Peking Union Medical College

Fudan University

Central South University

First Affiliated Hospital of Chongqing Medical University

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Temperature Compensation Method Based on an Improved Firefly Algorithm Optimized Backpropagation Neural Network for Micromachined Silicon Resonant Accelerometers

Micromachines (2022)

Libin Huang Lin Jiang Liye Zhao Xukai Ding

The output of the micromachined silicon resonant accelerometer (MSRA) is prone to drift in a temperature-changing environment. Therefore, it is crucial to adopt an appropriate suppression method for temperature error to improve the performance of the accelerometer. In this study, an improved firefly algorithm-backpropagation (IFA-BP) neural network is proposed in order to realize temperature compensation. IFA can improve a BP neural network's convergence accuracy and robustness in the training process by optimizing the initial weights and thresholds of the BP neural network. Additionally, zero-bias experiments at room temperature and full-temperature experiments were conducted on the MSRA, and the reproducible experimental data were used to train and evaluate the temperature compensation model. Compared with the firefly algorithm-backpropagation (FA-BP) neural network, it was proven that the IFA-BP neural network model has a better temperature compensation performance. The experimental results of the zero-bias experiment at room temperature indicated that the stability of the zero-bias was improved by more than an order of magnitude after compensation by the IFA-BP neural network temperature compensation model. The results of the full-temperature experiment indicated that in the temperature range of -40 °C~60 °C, the variation of the scale factor at full temperature improved by more than 70 times, and the variation of the bias at full temperature improved by around three orders of magnitude.

Backpropagation

Firefly Algorithm

Robustness

Temperature coefficient

10.3390/mi13071054

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Citations (10)

Correlation between preoperative psychological personality traits of glioma patients and psychological distress in their primary caregivers

Clinical Neurology and Neurosurgery (2022)

Liying Zhang Lin Jiang Chaoyi Chen Ke Wang Wei Xiang

Hypomania

10.1016/j.clineuro.2022.107144

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Citations (2)

Correction to: Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model

Translational Psychiatry (2023)

Yanmin Luo Qian Xiao Jin Wang Lin Jiang Menglan Hu

The original version of this article contained an error.In the original file of Fig. 4g, the loading controls were accidentally mirror-image changed.The loading controls of Fig. 4g should be the same as the loading controls of Fig. 3c, because in the western blotting experiment, the two proteins came from the same piece of separation glue and shared the same loading controls.

Chronic Stress

10.1038/s41398-023-02465-8

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Growth Factor-Reinforced ECM Fabricated from Chemically Hypoxic MSC Sheet with Improved In Vivo Wound Repair Activity

BioMed Research International (2017)

Huicong Du Lin Jiang Wenxin Geng Jing Li Rui Zhang

MSC treatment can promote cutaneous wound repair through multiple mechanisms, and paracrine mediators secreted by MSC are responsible for most of its therapeutic benefits. Recently, MSC sheet composed of live MSCs and their secreted ECMs was reported to promote wound healing; however, whether its ECM alone could accelerate wound closure remained unknown. In this study, Nc-ECM and Cc-ECM were prepared from nonconditioned and CoCl 2 -conditioned MSC sheets, respectively, and their wound healing properties were evaluated in a mouse model of full-thickness skin defect. Our results showed that Nc-ECM can significantly promote wound repair through early adipocyte recruitment, rapid reepithelialization, enhanced granulation tissue growth, and augmented angiogenesis. Moreover, conditioning of MSC sheet with CoCl 2 dramatically enriched its ECM with collagen I, collagen III, TGF- β 1, VEGF, and bFGF via activation of HIF-1 α and hence remarkably improved its ECM’s in vivo wound healing potency. All the Cc-ECM-treated wounds completely healed on day 7, while Nc-ECM-treated wounds healed about 85.0%±8.6%, and no-treatment wounds only healed 69.8%±9.6% (p<0.05). Therefore, we believe that such growth factor-reinforced ECM fabricated from chemically hypoxic MSC sheet has the potential for clinical translation and will lead to a MSC-derived, cost-effective, bankable biomaterial for wound management.

Granulation tissue

10.1155/2017/2578017

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Citations (19)

Hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant effects of running exercise

Translational Psychiatry (2021)

Jin Wang Jing Tang Xin Liang Yanmin Luo Peilin Zhu

Abstract Running exercise was shown to have a positive effect on depressive-like symptoms in many studies, but the underlying mechanism of running exercise in the treatment of depression has not been determined. Parvalbumin-positive interneurons (PV + interneurons), a main subtype of GABA neurons, were shown to be decreased in the brain during the depression. PGC-1α, a molecule that is strongly related to running exercise, was shown to regulate PV + interneurons. In the present study, we found that running exercise increased the expression of PGC-1α in the hippocampus of depressed mice. Adult male mice with PGC-1α gene silencing in the hippocampus ran on a treadmill for 4 weeks. Then, depression-like behavior was evaluated by the behavioral tests, and the PV + interneurons in the hippocampus were investigated. We found that running exercise could not improve depressive-like symptoms or increase the gene expression of PV because of the lack of PGC-1α in the hippocampus. Moreover, a lack of PGC-1α in the hippocampus decreased the number and activity of PV + interneurons in the CA3 subfield of the hippocampus, and running exercise could not reverse the pathological changes because of the lack of PGC-1α. The present study demonstrated that running exercise regulates PV + interneurons through PGC-1α in the hippocampus of mice to reverse depressive-like behaviors. These data indicated that hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant actions of running exercise. Our results will help elucidate the antidepressant mechanism of running exercise and identify new targets for antidepressant treatment.

10.1038/s41398-021-01339-1

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Citations (24)

Analysing community work: Theory and practice Keith Popple (ed.)

Journal of Social Work (2017)

Lin Jiang

Community work

10.1177/1468017316674618

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Citations (0)

Familism

Springer eBooks (2019)