Aim: Epstein-Barr virus (EBV) is an infectious agent that affects more than 95% of the world’s population and is usually diagnosed through characteristic clinical findings, hematologic changes in complete blood counts, and atypical lymphocytes in peripheral smears. A definitive diagnosis requires serological confirmation of the EBV infection. This study intends to investigate the relationship between the mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT) values, which are platelet indices that can be used as markers of inflammation in different inflammatory diseases, and the EBV-associated infectious mononucleosis (IM) disease.Material and Methods: A total of 54 patients (30 males, 24 females) with EBV-associated infectious mononucleosis diagnosed at the Department of Pediatrics, University of Gaziantep University between January 2015 and June 2017 were retrospectively analyzed. Meanwhile, 68 age and gender-matched children were involved as the control group. White blood cell (WBC), hemoglobin (Hb), MPV, PDW and PCT values were compared across the patient and control group.Results: While the MPV values of the EBV-associated IM patient group were significantly high, the PDW values were significantly low (p0.001). The mean (WBC) counts of the IM patients were higher than those of the control group (p0.001). There was no significant difference between the groups in terms of PCT, platelet and Hb values. Conclusion: According to our findings, PDW and particularly MPV may be useful markers of inflammation during EBV-associated IM.

Mononucleosis

Mean platelet volume

10.5455/annalsmedres.2019.10.653

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Immune thrombocytopenic purpura following Varicella zoster infection

Journal of Clinical and Experimental Investigations (2011)

Ali Bay Ali Seçkin Yalçın Mehmet Enes Coşkun Hatice Uyanık Alper Dai

Although thrombocytopenia is a rarely observed complication following chickenpox, it can lead to serious bleeding problems. In order to underline rare hematologic complications of varicella infection and the importance of vaccination, here we reported a seven year old boy who developed severe thrombocytopenia during varicella infection and gave good response to intravenous immunoglobulin therapy.

Chicken Pox

Thrombocytopenic purpura

Purpura (gastropod)

10.5799/ahinjs.01.2011.01.0215

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Neonates Hearing Screening Results: A Comparison of Chirp and Click Stimuli with an Automated Auditory Brainstem Response Device

Cyprus Journal of Medical Sciences (2021)

Hüseyin Deniz Alper Yazıcı Mehmet Enes Coşkun

Automated Auditory Brain Response (AABR) devices are unique tools for neonate hearing screening programs.Contemporary utilization of AABR devices is based on two stimuli called chirp and click.The first study objective was to identify any possible differences in chirp and click stimulus results of the AABR devices in neonates.The second aim was to investigate any possible risk factor that could affect the results of each stimulus. MATERIAL and METHODSChirp and click stimuli were applied to each neonate using the AABR devices.Results were recorded automatically as pass or failed.Those with failed results were called after month for a retest.Hearing loss risk factors were obtained from the parents and caregivers. RESULTSTwenty-one of the fifty-eight chirp stimuli gave negative results on the AABR in the second AABR test.Twenty-nine of the seventy-six click stimuli on the AABR gave a failed result on retest.The most common risk factors were consanguineous marriage of parents (n=184), history of being admitted to the neonatal intensive care unit (n=119), and jaundice (n=102).In addition, hearing loss was not detected in any neonate and was therefore not considered to significantly affect the results of the chirp or click stimulus on the AABR. CONCLUSIONWe were unable to prove that the chirp stimulus could be replaced by the click stimuli in neonatal hearing screening using AABR device.

Stimulus (psychology)

Chirp

Auditory brainstem response

Auditory stimuli

10.5152/cjms.2020.1911

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Add-on therapy with dapagliflozin in routine outpatient care of type 2 diabetes patients from Turkey: a retrospective cohort study on HbA1c, body weight, and blood pressure outcomes

International Journal of Diabetes in Developing Countries (2021)

Derun Taner Ertuğrul Erdal Kan Çiğdem BAHADIR TURA Haci Bayram Tugtekin Hayati Ayakta

Dapagliflozin

Glycated hemoglobin

Discontinuation

10.1007/s13410-021-00954-4

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The effect of ventilation tube insertion to the health‐related quality of life in a group of children in Southeast Anatolia

Clinical Otolaryngology (2018)

Alper Yazıcı Mehmet Enes Coşkun

To demonstrate the influence of ventilation tube insertion to the quality of life in a group of children in Southeast Anatolia by Otitis Media 6-item (OM6) questionnaire.Patients who underwent ventilation tube insertion due to otitis media with effusion (OME) at Otorhinolaryngology Department of Gaziantep University between December 2016 and April 2017 were enrolled in this prospective study. All patients were evaluated with the OM-6 survey before operation and 6 weeks after surgery.The mean age of 45 patients out of 50 accounted for 67.64 ± 42.89 months with 27 (60%) males and 18 (40%) females. The numbers of preoperative and postoperative overall OM6 scores represented a significant improvement with 4.34 and 2.16, respectively. Moreover, each domain of OM6 (physical suffering, hearing loss, speech impairment, emotional distress, activity limitations and caregiver concerns) showed statistically significant difference.Ventilation tube insertion procedure provided a significant improvement in a group of children in Southeast Anatolia suffering from chronic OME in terms of Quality of Life (QOL) assessed by OM6. We believe that OM6 is a useful tool for evaluating the patients' health-related quality of life and for providing additional information to the caregivers' or families' enquiries regarding the consequences of surgical intervention.

10.1111/coa.13220

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Citations (8)

Çocuklarda Kan Gruplarının Brusella Enfeksiyonu ile İlişkisi

Çocuk Enfeksiyon Dergisi/Journal of Pediatric Infection (2022)

Hatice Uygun İbrahim Hakan Bucak Cüret Alev Mehmet Enes Coşkun Nurettin Erdem

Özgün Araştırma

10.5578/ced.20229703

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Horseshoe Kidney as a New Anomaly in Pagod Syndrome: Case Report

Turkiye Klinikleri Journal of Pediatrics (2013)

Onur Balcı Ercan Sivaslı Z. Şafak Taviloğlu Fatih Temel Yılmaz Sibel Arslan

Horseshoe kidney

Anomaly (physics)

Source

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Prevalence and characteristics of coronary artery anomalies in children with congenital heart disease diagnosed with coronary angiography

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology (2017)

Münevver Tuğba Temel Mehmet Enes Coşkun Osman Başpınar Abdullah T. Demiryürek

Aim of the present study was to determine the prevalence of coronary artery anomalies in children with congenital heart disease.Data of 1138 consecutive patients who were referred for cardiac catheterization and angiography for assessment of coronary anomaly between January 2005 and December 2009 were retrospectively analyzed. Total of 515 patients whose coronary arteries could be examined through left ventricle and aortic root injection were included in the study.Of 515 angiograms with visible coronaries, 42 patients (20 males, 22 females; mean age: 5.3±2.0 years) were found to have final diagnosis of coronary anomaly. Prevalence of coronary artery anomalies was 8.16% in this study. It was determined that 38 (90.4%) were anomalies of origination, 2 (4.8%) were anomalies of intrinsic coronary arterial anatomy, and 2 (4.8%) were anomalies of coronary termination. Most common coronary artery abnormality was anomalous origin of the right coronary artery from the left aortic sinus (16 patients; 38.1%), and the most common congenital heart disease was tetralogy of Fallot (18 patients; 42.9%).Recognizing variability of coronary artery anomalies is critical when considering surgical or interventional therapies in children with congenital heart disease.

Left coronary artery

Coronary arteries

Coronary artery anomaly

Cardiac catheterization

Aortic sinus

10.5543/tkda.2017.24162

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Citations (8)

Association of Brucella Infection with ABO Blood Groups in Children

Çocuk Enfeksiyon Dergisi/Journal of Pediatric Infection (2022)

Hatice Uygun İbrahim Hakan Bucak Cüret Alev Mehmet Enes Coşkun Nurettin Erdem

ÖzGiriş: Bruselloz dünya çapında en yaygın zoonotik enfeksiyondur.ABO kan grupları, bir dizi bulaşıcı ve bulaşıcı olmayan hastalıkla ilişkilendirilmiştir. Ancak çocuklarda Brucella enfeksiyonu oluşumunda kan gruplarının etkisinin

Association (psychology)

10.5578/ced.20229710

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