There is a large amount of literature discussing the issues regarding promotion and how important the key factors are.Most of the existing researches use the exact data to analyze problems, but there always exist various uncertainties in realworld problems.It is usually hard to define a traditional quantitative approach to solve these problems.Our research incorporates method to identify affecting promotion and to analyze the pairwise relationships of these factors via the relevant mathematical models.According to the results of this study, we conclude that employing the proposed approach to identify promoting to provide top managers with reference to draw up the marketing strategies.
Objective To explore the effect of artificial and computer-assisted cognitive training on visuospatial impairment.Methods 63 patients with visuospatial impairment were randomly assigned to artificial group(n=21),computer-assisted training group(n=21) and integration group(n=21).The artificial group received conventional cognitive training while the computer-assisted training group used computer to assist cognitive training,and the integration group combined computer with conventional cognitive training.All groups were assessed with Loewenstein Occupational Therapy Cognitive Assessment(LOTCA).Results All groups improved significantly after training(P0.001).There were no significant difference between 3 groups in visual perception,spatial perception,and motor praxis after training.Compared to the computer-assisted training group,the integration group and the artificial group improved more significantly in visuomotor organization after training.Conclusion Artificial cognitive training and computer-assisted training can effectively improve the cognitive function of patients with visuospatial impairment.
1.INTRODUCTIONFor the last ten years, information technology (IT) outsourcing has appeared as a necessity for enterprise contention. Progressive outsourcing is different from conventional outsourcing. In this regard, IT is principal to the procedure accomplishments and the management of progressive relationships in outsourcing. Both factors are filled with contests and often result in insufficient outcomes for e-commerce enterprises. With regard to IT outsourcing satisfaction, many views have been considered, such as e-commerce enterprise representatives, vendor representatives, the relationship of vendors and e-commerce enterprises, vendor capabilities, and cultural differences.The chief issue for IT clusters in enterprises is to understand how to handle such hardships to achieve better outsourcing satisfaction (Mani & Barua, 2015). IT outsourcing vendors have changed enterprises from insignificant users of outcomes to participators in value creation. Multitudinous enterprises try to involve groups in value creation, which is related to outsourcing satisfaction (Kohler, 2015). Value creation is conditional on complementary investments in social planning (SP), social positioning (SPO), environment scanning (EC), and customer participation (CP) with IT outsourcing vendors and electronic commerce (e-commerce) enterprises (Mani & Barua, 2015). It is important to recognize the role that social service organizations play between IT outsourcing vendors and e-commerce enterprises.Value creation has been introduced by Prahalad & Ramaswamy (2004). They suggest that service values are not created by manufacturers or suppliers alone, but by both entities working together with IT outsourcing vendors. Based on this construct, researchers have devised models to examine how values are created. For instance, Maglio & Spohrer (2008) use the value creation construct to clarify the essentials of service science, whereas Wu & Wu (2011) apply it to construct a service process structure. Dong et al. (2008) investigate the contextual relation of service failures in a value co-creation situation. Vargo et al. (2008) and Payne et al. (2008) construct models to study and perform value creation in service systems. Perks et al. (2012) study the value-creation process in car insurance industries through service creation. Ng et al. (2010) study enterprise-to-enterprise services by applying the value-creating structure. As it is an interrelated area, many studies concentrate on formulating research structures and measures for investigating value creation (Dong et al., 2008; Ng et al., 2010).Social planning and social positioning are enterprise strategies composed of corporate social responsibility (CSR) and stakeholder integration (SI) (Ferreira & Proenca, 2015). The levels of performance of social planning and social positioning can impact their competitive markets. CSR represents companies' unconditional enterprises implements that are planned to better community interests (Korschun, Bhattacharya, & Swain, 2014). Many enterprises include CSR itemizations in yearly narratives and on enterprise websites, underscoring its importance (Mishra & Modi, 2016; Servaes & Tamayo, 2013). Strategic social planning of an enterprise is related to CSR. Stakeholder integration plays an important role in strategic SPO. Social planning is the new way of ensuring continuous corporate development. SPO can be seen as outsourcing vendors' loyalties to e-commerce enterprises versus integrations to stakeholders (Nicolas, Jonathan, & Jonathan, 2015; Lockett et al., 2014).E-commerce enterprises have definite plans for the development of social initiatives. They measure the results of their social initiatives and are usually among the first to adapt their corporate practices to changing social expectations. External environment influences IT outsourcing vendors and e-commerce enterprises (e.g., partnerships). …
Abstract Background The SOD2 gene encodes an antioxidant enzyme, mitochondrial superoxide dismutase. SOD2 polymorphisms are of interest because of their potential roles in the modulation of free radical-mediated macromolecular damage during aging. Results We identified a new splice variant of SOD2 in human lymphoblastoid cell lines (LCLs). The alternatively spliced product was originally detected by exon trapping of a minigene in order to examine the consequences of an intronic polymorphism found upstream of exon 4 (nucleotide 8136, 10T vs 9T). Examination of the transcripts derived from the endogenous loci in five LCLs with or without the intron 3 polymorphism revealed low levels of an in-frame deletion of exon 4 that were different from those detected by the exon trap assay. This suggested that exon trapping of the minigene unmasked the effect of the 10T vs 9T polymorphism on the splicing of the adjacent exon. We also determined the frequencies of single nucleotide polymorphisms in a sample of US African-Americans and non-African-Americans ages 65 years and older who participated in the 1999 wave of the National Long Term Care Survey (NLTCS). Particularly striking differences between African-Americans and non-African-Americans were found for the frequencies of genotypes at the 10T/9T intron 3 polymorphism. Conclusion Exon trapping can unmask in vitro splicing differences caused by a 10T/9T intron 3 polymorphism. Given the recent evidence that SOD2 is in a region on chromosome 6 linked to susceptibility to hypertension, it will be of interest to investigate possible associations of this polymorphism with cardiovascular disorders.
Objective To explore the relationship between breastfeeding and diarrhoeal disease in infants.Methods The breastfeeding rate was compared between the case group and the control group by using case-control study;and the odds ratio(OR)was calculated.Results The breastfeeding rate of the control group was 56.83%,which was significantly higher than that of the case group(32.65%).The OR(95% CI)of the breastfeeding period 6 months,3～5 months,2 months and the OR of without breastfeeding,were 1.74(0.78,3.89),1.94(1.03,3.65),2.52(1.41,4.50),and 4.03(2.37,6.86)respectively.Conclusions The breastfeeding period of more than six successive months could reduce the diarrhoeal disease in infants,and hence six-month breastfeeding is necessary.
Summary Type IV secretion systems are virulence determinants in many bacteria and share extensive homology with many conjugal transfer systems. Although type IV systems and their homologues have been studied widely, the mechanism by which substrates are secreted remains unclear. In Agrobacterium , we show that type IV secretion substrates that lack signal peptides form a soluble complex in the periplasm with the virulence protein VirJ. Additionally, these proteins co‐precipitate with constituents of the type IV transporter: the VirB pilus and the VirD4 protein. Our findings suggest that the substrate proteins localized to the periplasm may associate with the pilus in a manner that is mediated by VirJ, and suggest a two‐step process for type IV secretion in Agrobacterium . Our analyses of protein–protein interactions in a variety of mutant backgrounds indicate that substrates are probably secreted independently of one another.
'/%3e%3cuse xlink:href='%23a' transform='rotate(23.036 .093 25.536)'/%3e%3cuse xlink:href='%23a' transform='rotate(45.87 1.273 16.18)'/%3e%3cuse xlink:href='%23a' transform='rotate(69.945 .996 12.078)'/%3e%3cuse xlink:href='%23a' transform='rotate(20.66 -19.689 31.932)'/%3e%3c/svg%3e)
'/%3e%3cuse xlink:href='%23a' transform='rotate(60)'/%3e%3ccircle r='17' fill='%23000095'/%3e%3ccircle r='15' fill='%23fff'/%3e%3c/svg%3e)