Arlind Batalli

University Clinical Centre

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Gani Bajraktari

University Clinical Center of Kosovo

Michael Y. Henein

Imperial College London

Pranvera Ibrahimi

University Clinical Center of Kosovo

Shpend Elezi

University Clinical Center of Kosovo

Afrim Poniku

University Clinical Centre

Ibadete Bytyçi

University Clinical Center of Kosovo

Edmond Haliti

University Clinical Center of Kosovo

Artan Bajraktari

Umeå University

Artan Ahmeti

University Clinical Center of Kosovo

Rina Tafarshiku

University of Prishtina

Cooperative Institutions

Assistance Publique – Hôpitaux de Paris

University Clinical Center of Kosovo

Istituti di Ricovero e Cura a Carattere Scientifico

Inserm

Sorbonne Université

Centro Cardiologico Monzino

National and Kapodistrian University of Athens

KU Leuven

Centro de Investigación en Red en Enfermedades Cardiovasculares

Centro de Investigación Biomédica en Red

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Premature myocardial infarction: A population-based cohort study

Atherosclerosis (2023)

Ibadete Bytyçi Dua Shita Anida Ferati Arlind Batalli Rita Leka

Dyslipidemia

10.1016/j.atherosclerosis.2023.06.309

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Poster Session 4: Friday 9 December 2011, 14:00-18:00 * Location: Poster Area

European Journal of Echocardiography (2011)

M. Wang Gan‐Xin Yan Wensheng Yue Chetverikov SIu Hung‐Fat Tse

10.1093/ejechocard/jer216

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Different determinants of exercise capacity in HFpEF compared to HFrEF

Cardiovascular Ultrasound (2017)

Arlind Batalli Pranvera Ibrahimi Ibadete Bytyçi Artan Ahmeti Edmond Haliti

Quality of life is as important as survival in heart failure (HF) patients. Controversies exist with regards to echocardiographic determinants of exercise capacity in HF, particularly in patients with preserved ejection fraction (HFpEF). The aim of this study was to prospectively examine echocardiographic parameters that correlate and predict functional exercise capacity assessed by 6 min walk test (6-MWT) in patients with HFpEF.In 111 HF patients (mean age 63 ± 10 years, 47% female), an echo-Doppler study and a 6-MWT were performed in the same day. Patients were divided into two groups based on the 6-MWT distance (Group I: ≤ 300 m and Group II: >300 m).Group I were older (p = 0.008), had higher prevalence of diabetes (p = 0.027), higher baseline heart rate (p = 0.004), larger left atrium - LA (p = 0.001), longer LV filling time - FT (p = 0.019), shorter isovolumic relaxation time (p = 0.037), shorter pulmonary artery acceleration time - PA acceleration time (p = 0.006), lower left atrial lateral wall myocardial velocity (a') (p = 0.018) and lower septal systolic myocardial velocity (s') (p = 0.023), compared with Group II. Patients with HF and reduced EF (HFrEF) had lower hemoglobin (p = 0.007), higher baseline heart rate (p = 0.005), higher NT-ProBNP (p = 0.001), larger LA (p = 0.004), lower septal s', e', a' waves, and septal mitral annular plane systolic excursion (MAPSE), shorter PA acceleration time (p < 0.001 for all), lower lateral MAPSE, higher E/A & E/e', and shorter LVFT (p = 0.001 for all), lower lateral e' (p = 0.009), s' (p = 0.006), right ventricular e' and LA emptying fraction (p = 0.012 for both), compared with HFpEF patients. In multivariate analysis, only LA diameter [2.676 (1.242-5.766), p = 0.012], and diabetes [0.274 (0.084-0.898), p = 0.033] independently predicted poor 6-MWT performance in the group as a whole. In HFrEF, age [1.073 (1.012-1.137), p = 0.018] and LA diameter [3.685 (1.348-10.071), p = 0.011], but in HFpEF, lateral s' [0.295 (0.099-0.882), p = 0.029], and hemoglobin level [0.497 (0.248-0.998), p = 0.049] independently predicted poor 6-MWT performance.In HF patients determinants of exercise capacity differ according to severity of overall LV systolic function, with left atrial enlargement in HFrEF and longitudinal systolic shortening in HFpEF as the the main determinants.

Angiology

10.1186/s12947-017-0103-x

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OP-015 RELATIONSHIP BETWEEN BODY MASS INDEX AND LEFT VENTRICULAR HYPERTROPHY IN ASYMPTOMATIC ADOLESCENTS

International Journal of Cardiology (2012)

A.B. Kepuska Arlind Batalli M. Zejnullahu M. Shala Mehmedali Azemi

10.1016/s0167-5273(12)70009-8

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Smoking and Hypertriglyceridemia Predict ST-Segment Elevation Myocardial Infarction in Kosovo Patients with Acute Myocardial Infarction

Clinics and Practice (2024)

Afrim Poniku Arlind Batalli Dua Shita Zarife Rexhaj Arlind Ferati

Background: Myocardial infarction (MI), presented as ST-segment elevation MI (STEMI) and non-ST-segment elevation MI (NSTEMI), is influenced by atherosclerosis risk factors. Aim: The aim of this study was to assess the patterns of presentation of patients with acute MI in Kosovo. Methods: This was a cross-sectional study conducted at the University Clinical Center of Kosovo, which included all patients hospitalized with acute MI over a period of 7 years. Results: Among the 7353 patients admitted with acute MI (age 63 ± 12 years, 29% female), 59.4% had STEMI and 40.6% had NSTEMI. The patients with NSTEMI patients less (48.3% vs. 54%, p < 0.001), but more of them had diabetes (37.8% vs. 33.6%, p < 0.001), hypertension (69.6% vs. 63%, p < 0.001), frequently had a family history of coronary artery disease (CAD) (40% vs. 38%, p = 0.009), and had more females compared to the patients with STEMI (32% vs. 27%, p < 0.001). The patients with NSTEMI underwent less primary percutaneous interventions compared with the patients with STEMI (43.6% vs. 55.2%, p < 0.001). Smoking [1.277 (1.117–1.459), p ˂ 0.001] and high triglycerides [0.791 (0.714–0.878), p = 0.02] were independent predictors of STEMI. Conclusions: In Kosovo, patients with STEMI are more common than those with NSTEMI, and they were mostly males and more likely to have diabetes, hypertension, and a family history of CAD compared to those with NSTEMI. Smoking and high triglycerides proved to be the strongest predictors of acute STEMI in Kosovo, thus highlighting the urgent need for optimum atherosclerosis risk control and education strategies.

10.3390/clinpract14030091

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Total isovolumic time predict limited exercise capacity in male patients with heart failure, but not in female

Cardiologia Croatica (2013)

Arlind Batalli Gani Bajraktari Ilir Kurtishi Nehat Rexhepaj Rina Tafarshiku

Aim:The aim of this study was to investigate the impact of gender on the prediction of limited exercise capacity in heart failure (HF) patients assessed by 6 minute walk test (6-MWT).Methods: In 147 HF patients (mean age 61 ±11 years, 50.3% male), a 6-MWT and a Doppler echocardiographic study were performed on the same day.Conventional cardiac measurements were obtained as well as global LV dyssynchrony was indirectly assessed using total isovolumic time -t-IVT [in s/min; calculated as: 60 -(total ejection time -total filling time)] and Tei index (t-IVT/ejection time).Patients were divided into two groups according to gender, which were again divided into two subgroups based on the 6-MWT distance (Group I: 300m, and Group II: >300m).Results: Female patients were younger (p=0.02), and had higher left ventricular (LV) ejection fraction -EF (p=0.007)but with similar 6 MWT distance to male patients (p=68).Group I male patients had lower hemoglobin level (p=0.02) and lower EF (p=0.03),compared with Group II, but none of the clinical or echocardiographic variables differed between groups in female patients.In multivariate analysis, only t-IVT [0.699 (0.552-0.886), p=0.003], and LV EF [0.908 (0.835-0.987), p=0.02] in males, and NYHA functional class [4.439 (2.213-16.24),p=0.02] in females independently predicted poor 6-MWT distance (<300m).Conclusion: Despite similar limited exercise capacity, gender determines the pattern of underlying cardiac disturbances; ventricular dysfunction in males and subjective NYHA class in female heart failure patients.

10.15836/ccar.2013.189

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The Rationale and Design of the KOSovan Acute Coronary Syndrome (KOS-ACS) Registry

Diagnostics (2024)

Gani Bajraktari Shpend Elezi Ibadete Bytyçi Pranvera Ibrahimi Genc Abdyli

The KOSovan Acute Coronary Syndrome (KOS-ACS) Registry is established as a prospective, continuous, nationwide, web-based registry that is operated online. The KOS-ACS registry is designed with the following objectives: (1) to obtain data on the demographic, clinical, and laboratory characteristics of ACS patients treated in Kosovo; (2) to create a national database with information on health care in ACS patients treated in Kosovo; (3) to identify the national features of associations between ACS characteristics and clinical outcomes, including mortality, complications, the length of hospital stay, and the quality of clinical care; and (4) to propose a practical guide for improving the quality and efficiency of ACS treatment in Kosovo. The Kosovo Society of Cardiology and University of Prishtina will be responsible for the development of the KOS-ACS registry and centralized data analysis at the national level. The KOS-ACS Registry will enroll all patients admitted, at any of the registered clinical centers, with the diagnosis of ACS and who will be clinically managed at any of the Kosovo hospitals. Data on patient demographics, clinical characteristics, previous and hospital drug treatment, and reperfusion therapy will be collected. The type of ACS (unstable angina, NSTEMI, or STEMI) will also be clearly defined. The time from first medical contact to balloon inflation (FMC-to-balloon) and door-to-ballon time will be registered. In-hospital death and complications will be registered. Data on the post-hospital primary outcome (MACE: cardiac death, all-cause mortality, hospitalization, stroke, need for coronary revascularization) of patients, at 30 days and 1 year, will be included in the registry.

Unstable angina

Mace

10.3390/diagnostics14141486

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Predictors of subclinical atherosclerosis in asymptomatic healthy non-diabetic postmenopausal women

Atherosclerosis (2024)

Jehona Ismaili Pranvera Ibrahimi Venera Berisha‐Muharremi Mimoza Berbatovci‐Ukimeraj Nora Istrefi

Subclinical infection

10.1016/j.atherosclerosis.2024.117715

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Echocardiography: golden method in the diagnosis of congenital heart anomalies.

Cardiologia Croatica (2015)

Arbnore Batalli-Këpuska Ramush Bejiqi Arlind Batalli

echocardiography: golden method in the diagnosis of congenital heart anomaliesIntRoductIon: Congenital heart abnormalities are fairly common anomaly, that are numbered in second place after urinary tract anomalies.Large problem presents complex heart abnormalities due to lack of cardiological center in our country.The aim was to present the congenital heart abnormalities in the period January-June 2013 at children aged 1-12 months.

10.15836/ccar.2015.62

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Predictors of subclinical atherosclerosis in asymptomatic healthy non‐diabetic postmenopausal women

Clinical Physiology and Functional Imaging (2024)

Jehona Ismaili Pranvera Ibrahimi Venera Berisha‐Muharremi Rona Karahoda Mimoza Berbatovci‐Ukimeraj

Abstract Background and Aim Cardiovascular disease progresses after menopause. Conventional risk factors, particularly diabetes, for atherosclerosis are well‐established predictors of phenotypic arterial disease. The aim of this study is to assess the predictors of subclinical atherosclerosis in asymptomatic non‐diabetic postmenopausal women. Methods This prospective study included 117 consecutive postmenopausal women (mean age 59 ± 7 years) referred from the outpatient Rheumatology Clinic of the University Clinical Centre of Kosovo, recruited between September 2021 and December 2022. Clinical, biochemical, carotid ultrasound and coronary CT angiography data were analysed. Subclinical atherosclerosis was diagnosed when plaque and/or carotid intima‐media thickness >1.00 mm were present. Results Women who had subclinical atherosclerosis had higher erythrocyte sedimentation ( p = 0.022), higher total cholesterol ( p = 0.013), higher CAC score ( p = 0.017), and higher prevalence of CAC > 100 HU and CAC > 400 HU ( p = 0.017 and p = 0.034, respectively) compared to those without subclinical atherosclerosis. Women who had mild coronary calcification (CAC score ≥10 HU) were older ( p = 0.005), in longer menopause ( p = 0.005), had thicker CIMT ( p = 0.008) with higher prevalence ( p = 0.03) compared to those with CAC score <10 HU. Women with moderate coronary calcification (CAC score ≥100 HU) had higher triglycerides, worse CIMT ( p = 0.005) with higher prevalence ( p = 0.039) compared to those with CAC score <100 HU. In multivariate analysis [odds ratio 95% confidence interval], age [1.101 (1.032–1.174), p = 0.037] and cholesterol [2.020 (1.225–3.331), p = 0.006] independently predicted the presence of subclinical atherosclerosis. Conclusions In addition to the impact of age, hypercholesterolaemia is an important predictor of subclinical atherosclerosis in non‐diabetic postmenopausal women.

Subclinical infection

Coronary atherosclerosis

Outpatient clinic

Intima-media thickness

10.1111/cpf.12920

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