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Joshua Bliesath

12

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Abstract 3765: Discovery and biological characterization of CX-8184, a potent inhibitor of protein kinase CK2

2012 Cancer Research
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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

2012 Cancer Cell
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CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy.

2012 Molecular Cancer Therapeutics
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Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells

2012 Cancer Letters
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Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer

2011 Molecular and Cellular Biochemistry
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Protein kinase CK2 modulates IL-6 expression in inflammatory breast cancer

2011 Biochemical and Biophysical Research Communications
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Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.

2011 Journal of Medicinal Chemistry
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A method for detecting and preventing negative RNA interference in preparation of lentiviral vectors for siRNA delivery

2009 RNA
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A novel RNAi library based on partially randomized consensus sequences of nuclear receptors: Identifying the receptors involved in amyloid β degradation

2006 Genomics
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A 96-Well Surrogate Survival Assay Coupled with a Special Short Interfering RNA Vector for Assessing Cancer Gene Targets with Enhanced Signal/Noise Ratio and Its Utility in HTS for Cancer Therapeutic Targets

2005 Assay and Drug Development Technologies
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Citations (12)