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Nitin H. Shirole

Cold Spring Harbor Laboratory

10

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380

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TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

2017 eLife
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Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization

2017 Nature Communications
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The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants

2016
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TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

2016 eLife
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Author response: TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

2016 eLife
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SRSF1-Regulated Alternative Splicing in Breast Cancer

2015 Molecular Cell
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A rapid and tunable method to temporally control Cas9 expression enables the identification of essential genes and the interrogation of functional gene interactions in vitro and in vivo.

2015 bioRxiv
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Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan

2014 Nucleic Acids Research
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Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function

2012 Nucleic Acids Research
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Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

2011 Journal of Visualized Experiments
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