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Kuo-Chi Cheng
Kuo-Chi Cheng
Merck & Co.
Biochemistry
Chemistry
Permeability (electromagnetism)
Absorption (pharmacology)
Substrate (chemistry)
3
Papers
48
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Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR.
2011
Biochemical Pharmacology
Li Xiao
Elliott Nickbarg
Wenyan Wang
Ann Thomas
Michael Ziebell
Winfred W. Prosise
Charles A. Lesburg
Shane Taremi
Valerie L. Gerlach
Hung V. Le
Kuo-Chi Cheng
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Citations (28)
The impact of protein on Caco-2 permeability of low mass balance compounds for absorption projection and efflux substrate identification
2010
Journal of Pharmaceutical and Biomedical Analysis
Tongtong Liu
Lee Jah Chang
Annette S. Uss
Inhou Chu
Richard A. Morrison
Lydia Wang
Dan Prelusky
Kuo-Chi Cheng
Cheng Li
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Citations (14)
Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors.
2010
Bioorganic & Medicinal Chemistry Letters
Latha G. Nair
Stephane Bogen
Sumei Ruan
Weidong Pan
Russel Pike
Xiao Tong
Kuo-Chi Cheng
Zhuyan Guo
Ronald J. Doll
F. George Njoroge
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Citations (6)
1