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Andree R. Bourgoyne
Andree R. Bourgoyne
Antagonist
Endothelin receptor
Biochemistry
Chemistry
Oral administration
3
Papers
134
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Discovery, Modeling, and Human Pharmacokinetics of N-(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl) -thiophene-2-carboxamide (TBC3711), a Second Generation, ETA Selective, and Orally Bioavailable Endothelin Antagonist
2004
Journal of Medicinal Chemistry
Chengde Wu
E. Radford Decker
Natalie Blok
Huong Bui
Tony J. You
Junmei Wang
Andree R. Bourgoyne
Vippra Knowles
Kurt L. Berens
George W. Holland
Tommy A. Brock
Richard A. Dixon
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Citations (96)
Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides: TBC3214, an ETA selective endothelin antagonist.
2001
Journal of Medicinal Chemistry
Chengde Wu
E. Radford Decker
Natalie Blok
Jian Li
Andree R. Bourgoyne
Huong Bui
Karin Keller
Vippra Knowles
Wen Li
Fiona Stavros
George W. Holland
Tommy A. Brock,†,‡ and
Richard A. Dixon
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Citations (21)
Endothelin Antagonists: Substituted Mesitylcarboxamides with High Potency and Selectivity for ETA Receptors1
1999
Journal of Medicinal Chemistry
Chengde Wu
E. Radford Decker
Natalie Blok
Huong Bui
Qi Chen
Bore Gowda Raju
Andree R. Bourgoyne
Vippra Knowles
Ronald J. Biediger
Robert V. Market
Shuqun Lin
Brian Dupre
Timothy P. Kogan
George W. Holland
and Tommy A. Brock
Richard A. Dixon
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Citations (17)
1