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Hiroshi Kodaira

Kyowa Hakko Kirin Co., Ltd.

6

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The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis

2016 Human Molecular Genetics
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Quantitative Investigation of the Brain-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters

2014 Drug Metabolism and Disposition
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Quantitative Evaluation of the Impact of Active Efflux by P-Glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier on the Predictability of the Unbound Concentrations of Drugs in the Brain Using Cerebrospinal Fluid Concentration as a Surrogate

2011 Journal of Pharmacology and Experimental Therapeutics
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MULTIPLE ORGANIC ANION TRANSPORTERS INVOLVED IN BLOOD-BRAIN BARRIER TRANSPORT

2009
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