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Zhihua Liu
Zhihua Liu
Bristol-Myers Squibb
Monoclonal antibody
Chemistry
Stereochemistry
Organic chemistry
Glutamic acid
3
Papers
14
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Impact of polysorbate 80 grade on the interfacial properties and interfacial stress induced subvisible particle formation in monoclonal antibodies
2020
Journal of Pharmaceutical Sciences
Coleman Vaclaw
Kimberly Merritt
Valerie Pringle
Neal Whitaker
Madhushree Gokhale
Thiago C. Carvalho
Duohai Pan
Zhihua Liu
Dilbir S. Bindra
Mehrnaz Khossravi
Mark S. Bolgar
David B. Volkin
Maria O. Ogunyankin
Prajnaparamita Dhar
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Citations (3)
Investigation of anomalous charge variant profile reveals discrete pH-dependent conformations and conformation-dependent charge states within the CDR3 loop of a therapeutic mAb.
2020
mAbs
Wenkui Lan
Joseph J. Valente
Andrew Ilott
Naresh Chennamsetty
Zhihua Liu
Joseph M. Rizzo
Aaron P. Yamniuk
Difei Qiu
Holly M. Shackman
Mark S. Bolgar
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Citations (5)
Cyclization of N-Terminal Glutamic Acid to pyro-Glutamic Acid Impacts Monoclonal Antibody Charge Heterogeneity despite Its Appearance as a Neutral Transformation
2019
Journal of Pharmaceutical Sciences
Zhihua Liu
Joseph J. Valente
Shujie Lin
Naresh Chennamsetty
Difei Qiu
Mark S. Bolgar
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Citations (6)
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