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Naomi S. Sprigg

Walter and Eliza Hall Institute of Medical Research

12

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1830

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Lineage commitment in mammary epithelium is regulated by type 2 cytokines and Stat6

2008 Breast Cancer Research
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352 Suppressor of cytokine signalling (SOCS)-5 regulates IL-4 activity via interaction with the IL-4 receptor and inhibition of JAK1 kinase activity

2008 Cytokine
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The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development

2007 Development
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The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability

2006 Molecular Cell
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Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling

2005 Proceedings of the National Academy of Sciences of the United States of America
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Genetic Deletion of Murine SPRY Domain-Containing SOCS Box Protein 2 (SSB-2) Results in Very Mild Thrombocytopenia

2005 Molecular and Cellular Biology
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SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

1999 Cell
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Citations (707)
SOCS proteins: Negative regulators of cytokine signal transduction.

1998 Blood
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Twenty proteins containing a C-terminal SOCS box form five structural classes

1998 Proceedings of the National Academy of Sciences of the United States of America
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Citations (660)