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Ketan J. Patel

Laboratory of Molecular Biology

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Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response

2021 Nature
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Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

2020 Nature
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FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

2020 Nature Structural & Molecular Biology
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FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination during DNA repair

2019 bioRxiv
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Structure of the Fanconi anaemia monoubiquitin ligase complex

2019 Nature
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Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

2018 Nature
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Of sizzling steaks and DNA repair

2017 Science
- Felix A. Dingler
- Ketan J. Patel
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Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

2017 Nature
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Do Mutational Dynamics in Stem Cells Explain the Origin of Common Cancers

2015 Cell Stem Cell
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Michael Neuberger (1953–2013)

2013 Science
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