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Damaris B. Skouras
Damaris B. Skouras
Inflammasome
Medicine
Interleukin
Inflammation
Receptor
5
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92
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Inhibition of the NLRP3 inflammasome by OLT1177 induces functional protection and myelin preservation after spinal cord injury.
2021
Experimental Neurology
Jesús Amo-Aparicio
Joana Garcia-Garcia
Maria Puigdomenech
Isaac Francos-Quijorna
Damaris B. Skouras
Charles A. Dinarello
Rubèn López-Vales
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The NLRP3 inflammasome inhibitor, OLT1177® , ameliorates experimental allergic asthma in mice.
2021
Allergy
Lars Lunding
Damaris B. Skouras
Christina Vock
Charles A. Dinarello
Michael Wegmann
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The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease.
2020
Proceedings of the National Academy of Sciences of the United States of America
Niklas Lonnemann
Shirin Hosseini
Carlo Marchetti
Damaris B. Skouras
Davide Stefanoni
Angelo DAlessandro
Charles A. Dinarello
Martin Korte
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Citations (27)
Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial
2020
Viola Klück
T.L.Th.A. Jansen
Matthijs Janssen
Antoaneta Comarniceanu
M. Efde
Isak W Tengesdal
Kiki Schraa
Maartje C. P. Cleophas
Curtis L. Scribner
Damaris B. Skouras
Carlo Marchetti
Charles A. Dinarello
Leo A. B. Joosten
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Citations (41)
OLT1177 (dapansutrile), a selective NLRP3 inflammasome inhibitor, ameliorates experimental autoimmune encephalomyelitis pathogenesis
2019
Frontiers in Immunology
Alba Sánchez-Fernández
Damaris B. Skouras
Charles A. Dinarello
Rubèn López-Vales
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Citations (24)
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