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Paul Feucht

Novartis

14

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425

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Synthesis and Structure–Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases

2020 Journal of Medicinal Chemistry
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Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold

2016 Bioorganic & Medicinal Chemistry Letters
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Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies.

2015 Journal of Medicinal Chemistry
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Development of Potent RSK Inhibitors as Biological Probes

2015
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Discovery of Potent and Selective RSK Inhibitors as Biological Probes.

2015 Journal of Medicinal Chemistry
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Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

2014 Clinical Cancer Research
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Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors.

2013 ACS Medicinal Chemistry Letters
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Novartis Evaluation of the ForteBio Octet RED: A Versatile Instrument for Direct Binding Experiments

2011
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Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.

2011 Bioorganic & Medicinal Chemistry Letters
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Citations (47)