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Ana Crespillo-Casado

University of Cambridge

17

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525

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ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B

2020 Molecular Cell
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ISRIB blunts the integrated stress response by allosterically antagonising the inhibitory effect of phosphorylated eIF2 on eIF2B

2020 bioRxiv
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Choice of PP1 catalytic subunit affects neither requirement for G-actin nor insensitivity to Sephin1 of PPP1R15A-regulated eIF2αP dephosphorylation

2018 bioRxiv
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A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.

2018 Journal of Biological Chemistry
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Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B

2018 Science
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Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, eIF2B

2017 bioRxiv
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PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

2017 eLife
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Author response: PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

2017 eLife
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Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells.

2016 PLOS ONE
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G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases

2015 eLife
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