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Wende Niforatos

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Uninjured Rats Dynamic Range Neurons in CFA-Treated and Selective TRPV1 Receptor Antagonist, on Wide Systemic and Site-Specific Effects of A-425619, a

2015
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Ganglion Neurons Mediated Ionic Currents in Dorsal Root - P2X Receptor

2015
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A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain.

2014 Journal of Neurophysiology
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Mechanistic Insights Into the Analgesic Efficacy of A-1264087, a Novel Neuronal Ca2+ Channel Blocker That Reduces Nociception in Rat Preclinical Pain Models

2014 The Journal of Pain
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Characterization of the triazine, T4, a representative from a novel series of CaV2 inhibitors with strong state-dependence, poor use-dependence, and distinctively fast kinetics.

2014 European Journal of Pharmacology
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A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats.

2012 Biochemical Pharmacology
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Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca2+ channel blockers with analgesic activity

2012 Bioorganic & Medicinal Chemistry
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An Automated Electrophysiological Assay for Differentiating CaV2.2 Inhibitors Based on State Dependence and Kinetics

2012 Assay and Drug Development Technologies
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Comparative analysis of inactivated-state block of N-type (Cav2.2) calcium channels

2011 Inflammation Research
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Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

2011 Pain
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