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Daniel Lucena-Agell

Spanish National Research Council

26

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223

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Identification of novel anti-cancer agents by the synthesis and cellular screening of a noscapine-based library.

2021 Bioorganic Chemistry
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Studies toward the Synthesis of an Oxazole-Based Analog of (-)-Zampanolide.

2021 Organic Letters
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Design, Synthesis, and in vitro Evaluation of Tubulin-Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Block.

2021 ChemMedChem
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N -alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity

2020 Cancer Cell International
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Tubulin-GDP.BeF complex

2020
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Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents

2019 European Journal of Medicinal Chemistry
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Author response: Structural model for differential cap maturation at growing microtubule ends

2019 eLife
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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.

2018 Nature Communications
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Aggregated Compound Biological Signatures Facilitate Phenotypic Drug Discovery and Target Elucidation.

2016 ACS Chemical Biology
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Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds

2016 Molecular Microbiology
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Citations (13)