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Brian W. Bigger
Brian W. Bigger
Manchester Academic Health Science Centre
Mucopolysaccharidosis
Biology
Substrate (chemistry)
Enzyme replacement therapy
Extracellular matrix
2
Papers
16
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Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA
2020
Embo Molecular Medicine
Helen Parker
Stuart M. Ellison
Rebecca J. Holley
Claire O'Leary
Aiyin Liao
Jalal Asadi
Emily Glover
Arunabha Ghosh
Simon A. Jones
Fiona L. Wilkinson
David Brough
Emmanuel Pinteaux
Herve Boutin
Brian W. Bigger
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Substrate accumulation and extracellular matrix remodelling promote persistent upper airway disease in mucopolysaccharidosis patients on enzyme replacement therapy
2018
PLOS ONE
Abhijit Ricky Pal
Jean Mercer
Simon A. Jones
Iain A. Bruce
Brian W. Bigger
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Citations (8)
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