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John J. Doyle
John J. Doyle
Merck & Co.
Renin–angiotensin system
Biochemistry
Chemistry
Enzyme
Biological activity
5
Papers
140
Citations
0.01
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Synthesis and use of 3-amino-4-phenyl-2-piperidones and 4-amino-2-benzazepin-3-ones as conformationally restricted phenylalanine isosteres in renin inhibitors
1992
Journal of Medicinal Chemistry
S. E. De Laszlo
Bruce L. Bush
John J. Doyle
William J. Greenlee
David Hangauer
Thomas A. Halgren
Robert J. Lynch
Terry W. Schorn
Peter K.S. Siegl
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Citations (56)
Design of Renin Inhibitors Containing Conformationally Restricted Mimetics of the P1-P1′ and P1 through P2′ Sites
1991
Advances in Experimental Medicine and Biology
Peter D. Williams
Linda S. Payne
Debra S. Perlow
M. Katharine Holloway
Peter K. S. Siegl
Terry W. Schorn
Robert J. Lynch
John J. Doyle
John F. Strouse
George P. Vlasuk
Karst Hoogsteen
James P. Springer
Bruce L. Bush
Thomas A. Halgren
Jan tenBroeke
William J. Greenlee
Anthony D. Richards
John Kay
Daniel F. Veber
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Citations (1)
Design and synthesis of P2-P1'-linked macrocyclic human renin inhibitors
1991
Journal of Medicinal Chemistry
Ann E. Weber
Thomas A. Halgren
John J. Doyle
Robert J. Lynch
Peter K. S. Siegl
William H. Parsons
William J. Greenlee
Arthur A. Patchett
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Citations (47)
1