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Douglas J. Sheffler
Douglas J. Sheffler
Discovery Institute
Chemistry
Biochemistry
Cancer research
Small molecule
Amyloid precursor protein
9
Papers
36
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Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia.
2021
Journal of Medicinal Chemistry
Nicole Bata
Apirat Chaikuad
Nicole A. Bakas
Allison S. Limpert
Lester J. Lambert
Douglas J. Sheffler
Lena M. Berger
Guoxiong Liu
Cunxiang Yuan
Li Wang
Yi Peng
Jing Dong
Maria Celeridad
Fabiana I. A. L. Layng
Stefan Knapp
Nicholas D.P. Cosford
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A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors
2020
Journal of Biological Chemistry
Celeste Romero
Lester J. Lambert
Douglas J. Sheffler
Laurent Jean Stephane De Backer
Dhanya Raveendra-Panickar
Maria Celeridad
Stefan Grotegut
Socorro Rodiles
John Holleran
Eduard Sergienko
Elena B. Pasquale
Nicholas D.P. Cosford
Lutz Tautz
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Metabotropic Glutamate Receptor 5 as a Target for the Treatment of Depression and Smoking: Robust Preclinical Data but Inconclusive Clinical Efficacy.
2018
Biological Psychiatry
Samuel A. Barnes
Douglas J. Sheffler
Svetlana Semenova
Nicholas Dp Cosford
Anton Bespalov
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Citations (20)
Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production
2017
Frontiers in Pharmacology
Karen S. Poksay
Douglas J. Sheffler
Patricia Spilman
Jesus Campagna
Barbara Jagodzinska
Olivier Descamps
Olivia Gorostiza
Alex Matalis
Michael Mullenix
Dale E. Bredesen
Nicholas Dp Cosford
Varghese John
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Citations (4)
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