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Tracy L. Hagemann

University of Wisconsin-Madison

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Alexander disease: models, mechanisms, and medicine.

2021 Current Opinion in Neurobiology
- Tracy L. Hagemann
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Antisense therapy in a new rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment

2021 bioRxiv
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Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform

2020 Human Mutation
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Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform.

2019 bioRxiv
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Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

2018 Nature Communications
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Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease

2018 Annals of Neurology
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Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes

2018 Cell Reports
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Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

2018 Nature
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An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease.

2016 The Journal of Neuroscience
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[11C]PBR28 imaging in a mouse model of Alexander disease

2015 The Journal of Nuclear Medicine
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