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Brigido Perdomo
Brigido Perdomo
Alkermes
Chemistry
Pharmacology
Drug carrier
Biochemistry
Microsphere
4
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200
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Vivitrex, an injectable, extended-release formulation of naltrexone, provides pharmacokinetic and pharmacodynamic evidence of efficacy for 1 month in rats.
2003
Neuropsychopharmacology
Raymond T. Bartus
Dwaine F. Emerich
Joyce Hotz
Marc Blaustein
Reginald L. Dean
Brigido Perdomo
Anthony S. Basile
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Citations (58)
Inhibitors of Cyclooxygenase-2, but Not Cyclooxygenase-1 Provide Structural and Functional Protection against Quinolinic Acid-Induced Neurodegeneration
2003
Journal of Pharmacology and Experimental Therapeutics
Heather Salzberg-Brenhouse
Er-Yun Chen
Dwaine F. Emerich
Sam Baldwin
Ken Hogeland
Sharon Ranelli
Denise Lafreniere
Brigido Perdomo
Leah Novak
Theodora Kladis
Karen Fu
Anthony S. Basile
Jeffrey H. Kordower
Raymond T. Bartus
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Citations (59)
Sustained release chemotherapeutic microspheres provide superior efficacy over systemic therapy and local bolus infusions.
2002
Pharmaceutical Research
Dwaine F. Emerich
Pamela Snodgrass
Denise Lafreniere
Reginald L. Dean
Heather C. Salzberg
Joanne Marsh
Brigido Perdomo
Mahin F. Arastu
Shelley R. Winn
Raymond T. Bartus
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Citations (42)
Bradykinin Modulation of Tumor Vasculature: II. Activation of Nitric Oxide and Phospholipase A2/Prostaglandin Signaling Pathways Synergistically Modifies Vascular Physiology and Morphology to Enhance Delivery of Chemotherapeutic Agents to Tumors
2001
Journal of Pharmacology and Experimental Therapeutics
Dwaine F. Emerich
Reginald L. Dean
Pamela Snodgrass
Denise Lafreniere
Mary Agostino
Tania Wiens
Hua Xiong
Brant P. Hasler
Joanne Marsh
Melissa Pink
Byong Su Kim
Brigido Perdomo
Raymond T. Bartus
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Citations (41)
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