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Akifumi Morimoto
Akifumi Morimoto
Chemistry
Receptor
Indazole
Pharmacology
Thiazole
5
Papers
67
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Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects
2017
Journal of Medicinal Chemistry
Yasuhiro Wada
Seiji Nakano
Akifumi Morimoto
Ken-ichi Kasahara
Takahiko Hayashi
Yoshio Takada
Hiroko Suzuki
Michiko Niwa-Sakai
Shigeki Ohashi
Mutsuhiro Mori
Takatsugu Hirokawa
Satoshi Shuto
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Citations (4)
Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3-Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects
2015
Journal of Medicinal Chemistry
Yasuhiro Wada
Hiromitsu Shirahashi
Taisuke Iwanami
Masami Ogawa
Seiji Nakano
Akifumi Morimoto
Ken-ichi Kasahara
Eiichi Tanaka
Yoshio Takada
Shigeki Ohashi
Mutsuhiro Mori
Satoshi Shuto
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Citations (14)
Hit-to-lead optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as a novel class of EP1 receptor antagonists
2013
Bioorganic & Medicinal Chemistry Letters
Masakazu Atobe
Kenji Naganuma
Masashi Kawanishi
Akifumi Morimoto
Ken-ichi Kasahara
Shigeki Ohashi
Hiroko Suzuki
Takahiko Hayashi
Shiro Miyoshi
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Citations (13)
SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists
2013
Bioorganic & Medicinal Chemistry Letters
Masakazu Atobe
Kenji Naganuma
Masashi Kawanishi
Akifumi Morimoto
Ken-ichi Kasahara
Shigeki Ohashi
Hiroko Suzuki
Takahiko Hayashi
Shiro Miyoshi
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Citations (17)
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