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Shilpa Sambashivan
Shilpa Sambashivan
Amgen
TREM2
Microglia
Molecular biology
Disease
Biology
4
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125
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Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
2021
Proceedings of the National Academy of Sciences of the United States of America
Daniel C. Ellwanger
Shoutang Wang
Simone Brioschi
Zhifei Shao
Lydia Green
Ryan Case
Daniel Yoo
Dawn Weishuhn
Palaniswami Rathanaswami
Jodi Bradley
Sara Rao
Diana Cha
Peng Luan
Shilpa Sambashivan
Susan Gilfillan
Samuel A. Hasson
Ian Foltz
Menno van Lookeren Campagne
Marco Colonna
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Citations (12)
TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer’s disease variant TREM2R47H on murine myeloid cell function
2018
Journal of Biological Chemistry
Qingwen Cheng
Jean Danao
Santosh Talreja
Paul H. Wen
Jun Yin
Ning Sun
Chi Ming Li
Danny Chui
David Tran
Samir Koirala
Hang Chen
Ian Foltz
Songli Wang
Shilpa Sambashivan
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Citations (41)
Molecular basis for the loss-of-function effects of the Alzheimer's disease–associated R47H variant of the immune receptor TREM2
2018
Journal of Biological Chemistry
Athena Sudom
Santosh Talreja
Jean Danao
Eric Bragg
Rob Kegel
Xiaoshan Min
Jason Richardson
Zhongqi Zhang
Nikolai A. Sharkov
Edoardo Marcora
Steve Thibault
Jodi Bradley
Steve Wood
Ai-Ching Lim
Hang Chen
Songli Wang
Ian Foltz
Shilpa Sambashivan
Zhulun Wang
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Citations (49)
Beltless Translocation Domain of Botulinum Neurotoxin A Embodies a Minimum Ion-conductive Channel
2012
Journal of Biological Chemistry
Audrey Fischer
Shilpa Sambashivan
Axel T. Brunger
Mauricio Montal
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Citations (23)
1