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Dominik Wernic

Boehringer Ingelheim

33

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1838

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Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIs.

2016 ACS Medicinal Chemistry Letters
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A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS).

2015 Bioorganic & Medicinal Chemistry Letters
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Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1

2014 ACS Medicinal Chemistry Letters
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Discovery of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for the potential treatment of chronic hepatitis C virus infection.

2014 Journal of Medicinal Chemistry
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Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.

2013 Bioorganic & Medicinal Chemistry Letters
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Preparation of Aminoalkyl Chlorohydrin Hydrochlorides: Key Building Blocks for Hydroxyethylamine-Based HIV Protease Inhibitors.

2010 ChemInform
- Pierre L. Beaulieu
- Dominik Wernic
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Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.

2001 Journal of Medicinal Chemistry
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2‘,6‘-Dimethylphenoxyacetyl: A New Achiral High Affinity P3-P2 Ligand for Peptidomimetic-Based HIV Protease Inhibitors

2000 Journal of Medicinal Chemistry
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Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease : Towards smaller inhibitors

2000 Bioorganic & Medicinal Chemistry Letters
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Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives

1999 Journal of Organic Chemistry
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Citations (22)