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Bingnan Gu

University of Texas MD Anderson Cancer Center

20

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KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

2020 Cancer Cell
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BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

2018 Nature Communications
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Super-enhancer impairment is a link between MLL4 inactivated lung tumors and their vulnerability to glycolysis pathway inhibition

2018 bioRxiv
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MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes

2018 Molecular Cell
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A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

2016 Nucleic Acids Research
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Histone methylation modifiers in cellular signaling pathways

2015 Cellular and Molecular Life Sciences
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Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-Mediated Degradation

2015 Journal of Biological Chemistry
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UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells

2014 Cancer Research
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Chromatin Effector Pygo2 Mediates Wnt-Notch Crosstalk to Suppress Luminal/Alveolar Potential of Mammary Stem and Basal Cells

2013 Cell Stem Cell
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Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells.

2012 Cell Cycle
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