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Katrin Rapakko

Oulu University Hospital

30

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BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells

2019 Human Molecular Genetics
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Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility

2017 Scientific Reports
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Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility.

2016 PLOS Genetics
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Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients

2013 Leukemia
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Heterozygous mutations in PALB2 cause DNA replication and damage response defects

2013 Nature Communications
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Favorable therapeutic responses in newly diagnosed CML-CP patients induced by Dasatinib are reflected at the CD34+CD38+Progenitor cell but not at the CD34+CD38-Stem cell level : Results from randomized NordCML006 study

2011 Blood
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Low or undetectable numbers of Philadelphia chromosome-positive leukemic stem cells (Ph + CD34 + CD38 neg ) in chronic myeloid leukemia patients in complete cytogenetic remission after tyrosine kinase inhibitor therapy

2010 Leukemia
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The Proportion of Ph+CD34(+)CD38(neg) Leukemic Stem Cells In the Bone Marrow of Newly Diagnosed Patients with Chronic Myeloid Leukemia (CML) In Chronic Phase (CP) Is Variable and Correlates with High Sokal Risk, High Leukocyte Count, Low Hemoglobin Concentration, Splenomegaly and Increased Hematological Toxicity During Initial TKI Therapy Data From a Randomized Phase II NordCML006 Study

2010 Blood
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Germline alterations in the 53BP1 gene in breast and ovarian cancer families

2007 Cancer Letters
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Clinical first-trimester routine screening for Down syndrome in singleton pregnancies in northern Finland

2007 American Journal of Obstetrics and Gynecology
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