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Erno Wienholds

Princess Margaret Cancer Centre

35

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A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency

2019 Blood
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A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity.

2019 Leukemia
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ATP7B Variant c.1934T>G p.Met645Arg Causes Wilson Disease by Promoting Exon 6 Skipping

2019 bioRxiv
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Development of ERG-Enhancer Fluorescent Reporter System to Decipher Functional Heterogeneity in Leukemia

2018 Experimental Hematology
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Competitive in vivo screening of 64 candidate leukemia stem cell self-renewal regulators selects for genes protracting stem cell latency

2017 Experimental Hematology
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Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

2016 Cell Stem Cell
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Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

2015 Cancer Cell
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The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

2014 Nature
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Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion.

2014 Cell Stem Cell
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Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

2013 Nature Communications
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