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Pat Wheelan

Research Triangle Park

16

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Discovery of a Novel Series of Cyclic Urea as Potent CCR5 Antagonists.

2012 ChemInform
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Discovery of novel pyridyl carboxamides as potent CCR5 antagonists and optimization of their pharmacokinetic profile in rats.

2011 Bioorganic & Medicinal Chemistry Letters
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Synthesis and evaluation of 2-phenyl-1,4-butanediamine-based CCR5 antagonists for the treatment of HIV-1.

2011 Bioorganic & Medicinal Chemistry Letters
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Discovery of a novel series of cyclic urea as potent CCR5 antagonists

2011 Bioorganic & Medicinal Chemistry Letters
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Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1

2010 Bioorganic & Medicinal Chemistry Letters
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Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents.

2010 Bioorganic & Medicinal Chemistry Letters
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Blockade of X4-Tropic HIV-1 Cellular Entry by GSK812397, a Potent Noncompetitive CXCR4 Receptor Antagonist

2010 Antimicrobial Agents and Chemotherapy
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Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity

2010 Bioorganic & Medicinal Chemistry Letters
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4,4-Disubstituted Cyclohexylamine based CCR5 Chemokine Receptor Antagonists as Anti-HIV-1 agents

2009 Antiviral Research
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Imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV-1

2009 Bioorganic & Medicinal Chemistry Letters
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