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Pottayil Govindan Nair Sasikumar

Lund University

31

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170

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PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.

2021
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Abstract 4148: An orally bioavailable small molecule antagonist of TIM-3 signaling pathway shows potent anti-tumor activity

2019 Cancer Research
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A rationally designed peptide antagonist of the PD-1 signaling pathway as an immunomodulatory agent for cancer therapy

2019 Molecular Cancer Therapeutics
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Abstract B006: Functional antagonism of VSIG8-mediated immune suppression by oral VISTA agents

2018 Molecular Cancer Therapeutics
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Small-Molecule Immune Checkpoint Inhibitors Targeting PD-1/PD-L1 and Other Emerging Checkpoint Pathways

2018 BioDrugs
- Pottayil Govindan Nair Sasikumar
- Murali Ramachandra
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Abstract B007: Potent antitumor activity of a novel and orally available small-molecule antagonist targeting the CD47/SIRPα pathway

2018 Molecular Cancer Therapeutics
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Abstract 1650: Targeting CD47- SIRPα interaction by novel peptide-based antagonists

2017 Cancer Research
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Small-molecule antagonists of the immune checkpoint pathways: concept to clinic

2017 Future Medicinal Chemistry
- Pottayil Govindan Nair Sasikumar
- Murali Ramachandra
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Anti-PD-L1 peptide improves survival in sepsis

2017 Journal of Surgical Research
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Abstract A36: CA-170, an oral small molecule PD-L1 and VISTA immune checkpoint antagonist, promotes T cell immune activation and inhibits tumor growth in pre-clinical models of cancer

2017 Cancer immunology research
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