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Michael A. Lisio

McGill University

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Nelfinavir induces cytotoxicity towards high-grade serous ovarian cancer cells regardless of platinum sensitivity, involving induction of the unfolded protein response, modulation of protein synthesis, DNA damage, lysosomal impairment, and potentiation of toxicity caused by proteasome inhibition

2021 bioRxiv
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Abstract A74: The HIV protease inhibitor nelfinavir, alone or in combination with the proteasome inhibitor bortezomib, is cytotoxic to high-grade serous ovarian cancer cells regardless of platinum sensitivity

2020 Clinical Cancer Research
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